摘要
目的探讨湿润烧伤膏联合丹红注射液治疗糖尿病足的临床疗效。方法选择2013年1月至2017年9月黄石市第五医院烧伤整形科收治的50例糖尿病足患者作为研究对象,并按照随机数表法将其随机分为治疗组(25例)和对照组(25例),其中治疗组患者在调节血糖及血压、抗感染等全身综合治疗的同时,采用湿润烧伤膏联合丹红注射液予以治疗;对照组患者在调节血糖及血压、抗感染等全身综合治疗的同时,采用凡士林油纱予以治疗。对比观察两组患者间歇性跛行与疼痛的改善情况、治疗30 d时的临床疗效及创面愈合时间。结果治疗30 d时,治疗组患者间歇性跛行评分为(18.12±2.51)分、疼痛评分为(2.82±1.42)分,对照组患者间歇性跛行评分为(10.25±2.48)分、疼痛评分为(4.15±1.46)分,两组对比,P均<0.05,差异具有统计学意义;治疗30 d时,治疗组患者治疗有效率为92.0%,对照组患者治疗有效率为60.0%,两组对比,P<0.05,差异具有统计学意义;最终两组患者创面均完全愈合,其中治疗组患者的创面愈合时间为(28.08±5.86)d,对照组患者的创面愈合时间为(38.31±4.69)d,两组对比,P<0.05,差异具有统计学意义。结论湿润烧伤膏联合丹红注射液可有效促进糖尿病足创面的愈合,缩短创面愈合时间,改善间歇性跛行与疼痛程度,疗效显著,临床应用价值较高。
Objective To investigate the clinical efficacy of MEBO combined with Danhong injection in the treatment of diabetic foot.Methods A total of 50 diabetic foot patients,admitted to the Department of Burn and Plastic Surgery,Huangshi No.5 Hospital from January 2013 to September 2017 were divided,according to the random number table,into a treatment group(25 cases)and a control group(25 cases).While receiving the systemic comprehensive treatment such as blood sugar and blood pressure regulation,and anti-infection,the patients in the treatment group were treated with MEBO combined with Danhong injection,and in contrast the patients in the control group was treated with Vaseline gauze.The improvement of intermittent claudication and pain relief,and the clinical efficacy on day 30 of treatment and wound healing time were observed and compared between the two groups.Results On day 30 of treatment,in the treatment group the intermittent claudication score was(18.12±2.51)points and the pain score was(2.82 ±1.42)points whereas in the control group the intermittent claudication score was(10.25±2.48)points and the pain score was(4.15±1.46)points.The intermittent claudication score and pain score were respectively compared between the two groups and the results showed statistically significant differences(both P<0.05).On day 30 of treatment,the treatment effective rate was 92.0% in the treatment group and 60.0% in the control group,between which the comparison showed statistically significant diifference(P<0.05).At the end,the wounds of all patients were healed completely.The wound healing time in the treatment group was(28.08 ±5.86)d,which showed a statistically significant difference as compared with(38.31 ±4.69)d in the control group(P<0.05).Conclusion MEBO combined with Danhong injection can effectively promote the healing of diabetic foot wounds,shorten the wound healing time,improve intermittent claudication and relieve pain,presenting remarkable clinical efficacy and high clinical application value.
作者
汤俊
龙胜勇
Tang Jun;Long Shengyong(Department of Burn and Plastic Surgery,Huangshi No Hospital,Huangshi City,Hubei 435004,China)
出处
《中国烧伤创疡杂志》
2019年第4期240-244,共5页
The Chinese Journal of Burns Wounds & Surface Ulcers
