摘要
目的分析成功助孕的不孕症女性妊娠前后甲状腺功能指标,为不孕症的诊治提供支持。方法回顾性分析2016年10月至2018年9月在山东大学生殖医学研究中心就诊的386例成功助孕的不孕症女性妊娠前后甲状腺功能指标[促甲状腺激素(TSH)、游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)、抗甲状腺球蛋白抗体(A-TG)、抗甲状腺过氧化物酶抗体(A-TPO)]检测结果。结果386例成功助孕的不孕症女性妊娠前甲状腺功能异常率(13.99%)明显高于妊娠后(4.92%),差异有统计学意义(P<0.05);妊娠后FT3、FT4水平低于妊娠前,差异均有统计学意义(P<0.05)。结论良好的甲状腺功能更有利于不孕症女性的助孕治疗。不孕女性甲状腺功能异常应力求早发现、早诊断、早治疗,以得到良好的辅助生殖结局。
Objective To analyze the thyroid functional indexes before and after pregnancy in successfully assisted reproductive females with infertility to provide the support for the diagnosis and treatment of infertility.Methods The detection results of the thyroid functional indexes(TSH,FT3,FT4,A-TG,A-TPO)before and after pregnancy in 386 successfully assisted reproductive females with infertility in the Reproductive Medicine Center of Shandong University from October 2016 to September 2018 were retrospectively analyzed.Results The abnormal rate of thyroid function before pregnancy in successfully assisted reproductive females with infertility was 13.99%,which was significantly higher than 4.92%after pregnancy,and the difference was statistically significant(P<0.05).The FT3 and FT4 levels after pregnancy were lower than those before pregnancy with statistically significant difference(P<0.05).Conclusion Good thyroid function is conducive to the assisted pregnancy treatment in females with infertility.Infertile females with thyroid dysfunction should strive to early detection,early diagnosis and early treatment in order to achieve good assisted reproductive outcomes.
作者
满姗姗
刘义庆
高选
MAN Shanshan;LIU Yiqing;GAO Xuan(Research Center for Reproductive Medicine,Shandong University/National Research Center for Assisted Reproductive Technology and Reproductive Genetics/Key Laboratory for Reproductive Endocrinology of Ministry of Education/Shandong Provincial Key Laboratory of Reproductive Medicine,Jinan,Shandong 250001,China;Department of Clinical Laboratory,Affiliated Shandong Provincial Hospital,Shandong University,Jinan,Shandong 250021,China)
出处
《检验医学与临床》
CAS
2019年第16期2276-2278,共3页
Laboratory Medicine and Clinic
基金
山东省自然科学基金项目(ZR2016HM52)
