摘要
目的探究晚期上皮性卵巢癌患者与MRI DWI信号的相关性。方法回顾性分析85例晚期上皮性卵巢癌患者(试验组)和同期接受体检的85例健康志愿者(对照组)的临床资料,所有患者均行MRI扫描、DWI扫描和DCE-MRI扫描检查。试验组患者均接受手术病理检查确诊,根据FIGO分期标准进行临床分期的评估。比较2组受试者的ADC值差异和DCE-MRI定量参数。对试验组不同分期患者的ADC值差异和DCE-MRI定量参数进行比较。通过ROC曲线,对卵巢癌临床分期的诊断效能进行评价。结果试验组患者的DCE-MRI 3项参数均高于对照组(P<0.05),ADC值低于对照组(P<0.05)。随着卵巢癌患者临床分期的增高,DCE-MRI 3项参数逐渐增大,ADC值逐渐减小,各分期患者的扫描结果均有统计学差异(P<0.05)。晚期上皮性卵巢癌患者的临床分期与3项DCE-MRI参数呈正相关关系(P<0.05),与ADC值呈负相关关系(P<0.05)。Ktrans、Kep与ADC值对于晚期上皮性卵巢癌的诊断具有较高的特异度和敏感度,具有较高的诊断价值。结论晚期上皮性卵巢癌患者的临床分期与DCE-MRI定量参数呈正相关关系,与ADC值呈负相关关系,MRI扫描和DWI扫描在诊断晚期上皮性卵巢癌患者的临床分期方面具有较高的特异度和敏感度。
Objective To explore the correlation between MRI and DWI signals and patients with advanced epithelial ovarian cancer.Methods The clinical data of 85 patients with advanced epithelial ovarian cancer(experimental group)and 85 healthy volunteers(control group)were analyzed.All patients underwent MRI,DWI and DCE-MRI scans.All the patients in the trial group were diagnosed by surgical pathology,and the clinical staging was assessed according to the FIGO staging criteria.The clinical data of the 2 groups were analyzed,and the difference of ADC values and DCE-MRI quantitative parameters between the 2 groups were compared.The difference of ADC value and DCE-MRI quantitative parameters in different stages of trial group were compared.The diagnostic efficiency of ovarian cancer staging was evaluated by ROC curve.Results The 3 DCE-MRI parameters of the patients in the trial group were higher than those of the control group(P<0.05),and the ADC value was lower than that of the control group(P<0.05).With the increase of the clinical stage of ovarian cancer patients,the 3 DCE-MRI parameters gradually increased,and the ADC value decreased gradually.There were significant differences in the results of the patients in each stage(P<0.05).The clinical stages of advanced epithelial ovarian cancer were positively correlated with 3 DCE-MRI parameters(P<0.05),and negatively correlated with ADC values(P<0.05).The values of Ktrans,Kep and ADC have high specificity and sensitivity in the diagnosis of advanced epithelial ovarian cancer,and have high diagnostic value.Conclusion The clinical staging of patients with advanced epithelial ovarian cancer is positively correlated with DCE-MRI quantitative parameters and has a negative correlation with the value of ADC.MRI scan and DWI scan have higher specificity and sensitivity in the diagnosis of advanced epithelial ovarian cancer,and have high clinical value.
作者
潘静
张秋芳
PAN Jing;ZHANG Qiufang(The Fourth Hospital of Xi'an,Xi'an,710004)
出处
《实用癌症杂志》
2019年第9期1474-1477,共4页
The Practical Journal of Cancer
