摘要
目的对BPPV诊疗系统复位与手法复位治疗良性阵发性位置性眩晕(BPPV)的临床疗效研究进行Meta分析,为选择耳石复位的方法提供循证医学依据。方法检索BPPV诊疗系统复位(试验组)或手法复位(对照组)治疗BPPV的随机对照试验,筛选Jadad评分≥3分的文献,采用Stata 12.0软件进行Meta分析。结果共纳入7个随机对照试验807例患者,试验组复位1次、复位次日、复位后1周(包括1周治愈率和1周有效率)较对照组均有明显获益,差异具有统计学意义(RD=0.16,95%CI=0.06~0.26,P<0.05;RD=0.32,95%CI=0.20~0.43,P<0.05;RD=0.24,95%CI=0.09~0.40,P<0.05;RD=0.11,95%CI=0.06~0.15,P<0.05)。结论试验组的短期疗效优于对照组,建议临床上对BPPV患者采用BPPV诊疗系统进行复位。
[Objective]To evaluate the clinical effect of reduction with the diagnosis and treatment system for benign pa-roxysmal positional vertigo(BPPV)versus manual reduction in the treatment of BPPV through a Meta-analysis,and to provide an evidence-based medicine basis for canalith repositioning maneuvers.[Methods]Related databases were searched for randomized controlled trials(RCTs)on reduction with the BPPV diagnosis and treatment system(experimental group)or manual reduction(control group)in the treatment of BPPV,and the articles with a Jadad score of≥3 were screened out.Stata 12.0 was used to perform the meta-analysis.[Results]A total of 7 RCTs with 807 patients were included.Compared with the control group,the experimental group had significantly greater benefits after one reduction,on the next day after reduction,and at 1 week after reduction in terms of 1-week cure rate and 1-week response rate(risk difference(RD)=0.16,95%confidence interval(CI)=0.06-0.26,P<0.05;RD=0.32,95%CI=0.20-0.43,P<0.05;RD=0.24,95%CI=0.09-0.40,P<0.05;RD=0.11,95%CI=0.06-0.15,P<0.05).[Conclusion]The experimental group has a better short-term clinical outcome than the control group,and therefore,reduction with the BPPV diagnosis and treatment system is recommended for patients with BPPV in clinical practice.
作者
张鹏飞
高冠彩
赵丹
宋玉强
ZHANG Pengfei;GAO Guancai;ZHAO Dan;SONG Yuqiang(Department of Neurology,The Affiliated Hospital of Qingdao University,Qingdao 266003,China)
出处
《精准医学杂志》
2019年第4期341-344,349,共5页
Journal of Precision Medicine
基金
山东省医药卫生科技发展计划项目(2014WS0455)
关键词
BPPV诊疗系统
手法复位
物理治疗方法
良性阵发性位置性眩晕
META分析
BPPV diagnosis and treatment system
Manual reduction
Physical therapy modalities
Benign paroxysmal positional vertigo
Meta-analysis
