摘要
目的探讨面肌痉挛(HFS)微血管减压术(MVD)后延迟治愈的影响因素。方法选取2013年1月~2016年12月在广东省第二人民医院接受MVD术式治疗的HFS患者598例作为研究对象。其中延迟治愈97例作为观察组,立刻治愈501例作为对照组。比较两组的一般资料,并通过Logistic回归模型分析影响延迟治愈的危险因素。结果观察组病程≥5年、长期服用卡马西平、使用肉毒素及复合血管压迫的比例均高于对照组(P<0.05),两组性别、年龄等其他资料比较,差异无统计学意义(P>0.05)。Logistic回归分析结果显示,病程及术中血管压迫程度为影响延迟治愈的危险因素(OR=1.364、2.551,P<0.05)。结论HFS患者接受MVD术后延迟治愈的影响因素主要包括病程及术中血管压迫程度。
Objective To investigate the influencing factors of delayed cure of hemifacial spasm(HFS)after microvascular decompression(MVD).Methods A total of 598 patients with HFS who underwent MVD surgery at the Guangdong Second People′s Hospital from January 2013 to December 2016 were enrolled.Among them,97 cases of delayed cure were recorded as observation group.And 501 cases who were cured immediately recorded as control group.The general data of the two groups were compared and the risk factors of delayed cure was analyzed by Logistic regression analysis.Results The proportion of course of disease≥5 years,and the long-term use of Carbamazepine,botulinum toxin and composite vascular compression in the observation group were higher than those in the control group(P<0.05).There were no significant difference in gender,age and other data between the two groups(P>0.05).Logistic regression analysis showed that the course of disease and intraoperative vascular compression were the risk factors for delayed cure(OR=1.364,2.551,P<0.05).Conclusion The main influencing factors of the delayed cure after MVD in HFS patients include the course of disease and the degree of intraoperative vascular compression.
作者
王墨
梁兴波
刘佳文
罗国轩
张阳
张勇
WANG Mo;LIANG Xingbo;LIU Jiawen;LUO Guoxuan;ZHANG Yang;ZHANG Yong(Department of Neurosurgery,Guangdong Second People′s Hospital,Guangdong Province,Guangzhou,510317,China)
出处
《中国医药导报》
CAS
2019年第23期82-85,共4页
China Medical Herald
基金
广东省科技计划项目(2014A020212405)
关键词
面肌痉挛
微血管减压术
延迟治愈
影响因素
Hemifacial spasm
Microvascular decompression
Delayed cure
Influencing factor
