摘要
目的对比分析胃癌根治术D1与D2淋巴结清扫的临床效果。方法本文所选50例接受胃癌根治术治疗的胃癌伴肝硬化患者均为本院2008年2月至2013年5月所收治,将其中15例接受D1淋巴结清扫的患者设为D1组,将另外35例接受D2淋巴结清扫的患者设为D2组,对D1与D2淋巴结清扫的效果进行对比分析。结果在1年、3年以及5年存活率方面,D2组高于D1组,比较差异无统计学意义;在肝功能Child-Pugh分级A级患者并发症发生率方面,D1组与D2组比较差异无统计学意义;而在肝功能Child-Pugh分级B级、C级患者中,与D1组相比,D2组的肝肾功能障碍发生率显著上升(P<0.05)。结论胃癌根治术D1与D2淋巴结清扫的存活率相近;D2淋巴结清扫不会让肝功能Child-Pugh分级A级患者的并发症增加,而对于肝功能Child-Pugh分级B级、C级的患者来讲,则应谨慎选择D2淋巴结清扫。
Objective To compare and analyze the clinical effect of D1 and D2 lymph node dissection in radical gastrectomy for gastric cancer.Methods Fifty patients with gastric cancer and cirrhosis who underwent radical gastrectomy were treated in our hospital from February 2008 to May 2013.Fifteen of them underwent D1 lymph node dissection as group D1,and another 35 underwent D2 lymph node dissection as group D2.The effects of D1 and D2 lymph node dissection were compared and analysis.Results In terms of 1-year,3-year and 5-year survival rate,D2 group was higher than D1 group,and there was no statistically significant difference between groups;there was no significant difference in the incidence of complications between D1 group and D2 group in Child-Pugh grade A patients of liver function;but there was no significant difference between D1 group and D2 group in Child-Pugh grade B,C patients of liver function and D1 group.Compared with group D2,the incidence of liver and kidney dysfunction increased significantly(P<0.05).Conclusion The survival rate of D1 and D2 lymph node dissection in radical gastrectomy for gastric cancer is similar.D2 lymph node dissection will not increase the complications of patients with Child-Pugh grade A of liver function,but for patients with Child-Pugh grade B and C of liver function,D2 lymph node dissection should be carefully selected.
作者
黄超
刘智华
刘新
方佳
Huang Chao;Liu Zhihua;Liu Xin;Fang Jia(Department of Surgery,Yingtan People's Hospital,Yingtan,Jiangxi,335000,China)
出处
《当代医学》
2019年第27期10-12,共3页
Contemporary Medicine
基金
鹰潭市科技计划项目(SF201704)
关键词
胃癌根治术
淋巴结清扫
肝功能
Radical gastrectomy
Lymph node dissection
Liver function
