摘要
目的:探究丹参药材浸出物和有效成分的相关性。方法:按《中华人民共和国药典》方法对18批丹参药材的浸出物进行测定,采用高效液相色谱法对18批丹参药材有效成分的含量进行测定,在此基础上,对浸出物和有效成分含量进行相关性研究。结果:丹参浸出物含量越高,有效成分含量越高;浸出物含量越低,有效成分含量越低。结论:丹参有效成分含量和浸出物含量具同步相关性。建议《中华人民共和国药典》将丹参水溶性浸出物测定方法改为热浸法。
Objective: To investigate the correlation between the content of extractum and effective ingredients of Salvia miltiorrhizae radix et rhizoma. Methods: The extractum of 18 batches of Salvia miltiorrhizae radix et rhizoma was determined by the pharmacopoeia method. The content of effective ingredients in Salvia miltiorrhizae radix et rhizoma was determined by high performance liquid chromatography(HPLC). On the basis of this, the two sets of data were fitted to find out the relationships. Results: The results showed that when the content of extractum was higer, the content of effective ingredients was higher. The opposite was also true. Conclusion: This study provides a basis for the synchronous correlation of extractum and effective ingredients of salvia miltiorrhizae radix et rhizoma. The determination method of water-soluble extracts in Pharmacopoeia of the People’s Republic of China is suggested to use hot dipping method.
作者
吴彩霞
石典花
苏本正
戴衍朋
卢琪
张军
WU Cai-xia;SHI Dian-hua;SU Ben-zheng;DAI Yan-peng;LU Qi;ZHANG Jun(Jimo District Qingdao Hospital of Traditional Chinese Medicine,Qingdao 266200,China;Shandong University of Traditional Chinese Medicine,Jinan 250355,China;Shandong Academy of Chinese Medicine,Jinan 250014,China)
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2019年第9期4291-4294,共4页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
山东省重点研发计划(No.2016ZDJS07A22)
全国中药特色技术传承人才培训项目
山东省中医药科技发展计划项目(No.2015-173)~~
关键词
丹参
浸出物
含量测定
高效液相色谱法
相关性
中华人民共和国药典
Salvia miltiorrhizae radix et rhizoma
Extractum
Content determination
High performance liquid chromatography
Correlation
Pharmacopoeia of the People’s Republic of China
