摘要
目的探讨鼻内镜治疗慢性鼻-鼻窦炎后嗅觉障碍改善的危险因素。方法选取上海市第十人民医院86例(172侧)行鼻内镜治疗的慢性鼻-鼻窦炎患者为研究对象,手术前、术后6个月分别进行嗅觉功能测验,分析嗅觉障碍改善情况,并对一般资料(性别、年龄、文化程度、分型分期、病程、过敏因素、中隔偏曲、吸烟、饮酒)进行单因素及logistic多因素回归分析。结果86例患者术前嗅觉功能正常者22例,术前嗅觉功能障碍者61例术后改善44例,改善率72.13%。单因素分析显示性别、年龄、文化程度、病程、中隔偏曲、吸烟、饮酒与鼻内镜治疗后嗅觉障碍改善无关(P>0.05)。Logistic多因素回归结果显示,分型分期、过敏因素是鼻内镜治疗后嗅觉障碍改善的独立危险因素(P<0.05)。结论影响鼻内镜治疗后嗅觉障碍改善的独立危险因素为分型分期、过敏因素,在鼻内镜治疗基础上还需重视过敏因素的对症治疗。
Objective To explore the risk factors of olfactory dysfunction after endoscopic sinus surgery for chronic rhinosinusitis.Method 86 patients(172 sides)with chronic rhinosinusitis treated by nasal endoscopy in Shanghai Tenth People's Hospital were selected as subjects of study.The olfactory function tests were performed before and 6 months after operation to analyze the improvement of olfactory dysfunction.It was taken univariate and logistic multivariate regression analysis for general data(gender,age,culture degree,staging,course of disease,allergic factors,septum,smoking and drinking).Result 22 of 86 patients had normal olfactory function before operation.61 cases with olfactory dysfunction before operation improved 44 cases,with an improvement rate of 72.13%.Univariate analysis showed that sex,age,educational level,course of disease,septal deviation,smoking and drinking were not associated with the improvement of olfactory dysfunction after endoscopic sinus surgery(P>0.05).Logistic multivariate regression analysis showed that classification,stage and allergic factors were independent risk factors for improvement of olfactory dysfunction after endoscopic sinus surgery(P<0.05).Conclusion The independent risk factors for the recovery of olfactory dysfunction after nasal endoscopic treatment are typing,staging,and allergic factors.On the basis of nasal endoscopic treatment,it should pay attention to the symptomatic treatment of allergic factors.
作者
于艳
蔡晓菁
YU Yan;CAI Xiaojing(Department of Otolaryngology,Kunshan Second People's Hospital,Jiangsu Province,215300,China)
出处
《中国中西医结合耳鼻咽喉科杂志》
2019年第5期348-351,共4页
Chinese Journal of Otorhinolaryngology in Integrative Medicine
关键词
慢性鼻-鼻窦炎
鼻内镜
嗅觉障碍
危险因素
Chronic rhinosinusitis
nasal endoscopy
olfactory dysfunction
risk factors
