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不同标本类型对肺结核病原体检测的临床价值 被引量:3

The clinical value of different types of specimen for detection of mycobacterium tuberculosis DNA
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摘要 目的探讨不同标本类型(支气管灌洗液、痰液、血液)对肺结核分枝杆菌核酸(TB DNA)检测的临床价值。方法收集132例肺结核患者的支气管灌洗液,痰液,血液标本,分别进行TB DNA的检测。结果132例患者的支气管灌洗液、痰液及血液标本分别检出TB DNA阳性结果为123例、94例、5例,检出率分别为93.2%、71.2%、3.8%。三种不同标本类型检出的TB DNA阳性结果,支气管灌洗液阳性率高于痰液和血液,痰液阳性率高于血液(P<0.01)。结论三种临床常用标本类型,支气管灌洗液针对肺结核分枝杆菌的检出率最高,在肺结核的诊断及治疗效果监测方面值得推广运用。 Objective To investigate the clinical value of different type of specimens(bronchial lavage fluid,sputum or blood)for detection of mycobacterium tuberculosis DNA(TB DNA).Methods We collected samples of bronchial lavage fluid,sputum and blood from 132 patients for detection of TB DNA.Results The positive detections of the bronchial lavage fluid,sputum and blood of 132 patients were 123,94 and 5,respectively and the positive rate were 93.2%,71.2%and 3.8%,respectively.The positive rate of bronchial lavage fluid was higher than sputum and blood and sputum was higher than blood(P<0.01).Conclusion The specimen with highest positive rate is bronchial lavage fluid in three type specimens.It is worth popularizing and applying in the diagnosis and therapeutic effect monitoring for tuberculosis.
作者 杜秋蓉 杜笠 胡琼英 刘祥琴 DU Qiu rong;DU li;HU Qiong ying;LIU Xiang qin(Clinical Laboratory,Chengdu University of TCM,Chengdu 610075,China;Clinical Laboratory,Chengdu Tianfu New District People's Hospital,Chengdu 610213,China;Clinical Laboratory,Sichuan Academy of Medical Sciences&Sichuan Provincial People's Hospital,Chengdu 610072,China)
出处 《实用医院临床杂志》 2019年第6期157-159,共3页 Practical Journal of Clinical Medicine
关键词 肺结核 结核分枝杆菌 荧光PCR 标本类型 Tuberculosis Mycobacterium tuberculosis PCR specimen type
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