摘要
目的:分析肠易激综合征患者运用当归芍药散合四逆散加减治疗的临床效果。方法 :随机选取我院2016年7月-2018年7月肠易激综合征患者100例作为实验对象,分为对照组(n=50),实验组(n=50),对照组采用马来酸曲美布汀进行治疗,实验组采用当归芍药散合四逆散加减法进行治疗,对比两组患者临床效果。结果:两组患者经过治疗之后,乏力、便秘、腹泻、腹痛评分均较治疗之前有明显下降,实验组下降更为明显,差异具有统计学意义,P<0.05。两组患者经过治疗之后IL-8、IL-10、TNF-α水平均有所改善,实验组改善效果更佳,差异具有统计学意义,P<0.05。两组患者经过治疗之后,HAMA及HAMD评分均有所下降,实验组下降更为明显。差异具有统计学意义,P<0.05。结论:肠易激综合征患者运用当归芍药散合四逆散加减治疗的临床效果显著,值得推广。
Objective: To analyze the clinical effect of Danggui Sini powder combine modified Sinni powder in patients with irritable bowel syndrome. Methods: 100 patients with irritable bowel syndrome from July 2016 to July 1818 in our hospital were randomly selected as the experimental subjects(n=50) and the experimental group(n=50). The control group was treated with trimebutine maleate. The experimental group was treated with Danggui Sini powder combine modified Sinni powder. The clinical effects of the two groups of patients were compared. RESULTS: Aftertreatment, the scores of fatigue, constipation, diarrhea and abdominal pain were significantly lower than those before treatment. The decrease in the experimental group was more significant, and the difference was statistically significant(P<0.05). The levels of IL-8, IL-10 and TNF-α were improved in both groups after treatment. The improvement effect of the experimental group was better, and the difference was statistically significant(P<0.05). After treatment, the HAMA and HAMD scores decreased in both groups, and the decline in the experimental group was more pronounced.The difference was statistically significant(P<0.05). Conclusion: The clinical effect of Danggui Sini powder combine modified Sinni powder in patients with irritable bowel syndrome is significant and worthy of promotion.
作者
付勇刚
FU Yonggang(Direct Hospital of Hubei Province,Hubei Wuhan 430071,China)
出处
《中医药临床杂志》
2019年第10期1961-1963,共3页
Clinical Journal of Traditional Chinese Medicine
关键词
当归芍药散
四逆散
加减治疗
肠易激综合征
临床效果
Danggui Shaoyao San
Sini San
Addition and subtraction treatment
Irritable bowel syndrome
Clinical effect
