摘要
目的评价介入封堵术治疗先天性卵圆孔未闭致偏头痛的临床疗效。方法选取2014年6月-2018年8月在新疆维吾尔自治区中医医院心内科住院,诊断为偏头痛,经心脏超声及食道超声或右心声学造影确诊伴有卵圆孔未闭的患者95例,并在我科接受介入封堵术治疗,采取自身对照试验研究,术后3月后采用电话随访,术前术后分别行HIT-6评分对偏头痛症状进行评分量化,比较封堵术前后头痛症状改善情况。结果有93例患者手术成功,有2例封堵失败,无手术相关并发症,术前的HIT-6评分为56~74(60±5)分,术后的HIT-6评分为35~55(39±8)分,差异有统计学意义(P<0.05)。术后3月复查TTE显示封堵器位置良好,右心声学造影提示78例分流消失,15例仍有少量残余分流(5~10个微泡)。结论卵圆孔未闭封堵术可以明显缓解先天性卵圆孔未闭致偏头痛患者的头痛症状。
Objective To evaluate the clinical efficacy of interventional occlusion in the treatment of migraine caused by congenital foramen ovale.Methods 95 cases of patients who were admitted and were diagnosed of migraine in Xinjiang Uygur autonomous region hospital of traditional Chinese medicine from June 2014 to August 2018 were chosen as subjects.All cases were confirmed to suffer from patent foramen ovale by the cardiac ultrasound and ultrasound of the esophagus or angiography of right heart.All cases were treated with interventional closure,case-control study were carried out.Three months after the operation,follow-up by telephone was conducted.Before and after the operation,migraine symptoms were quantified by hit-6 score,and the improvement of headache symptoms after the operation of plugging was compared.Results Operation in ninety-three patients were successful,2 cases had failed closure and no surgical-related complications.The preoperative HIT-6 score was 56-74(60±5)points,and the postoperative HIT-6 score was 35-55(39±8)points,the difference was statistically significant(P<0.05).The TTE showed a good position in the occluder after 3 months of operation.Right heart echography showed that 78 cases of shunt disappeared,and 15 cases still had a small amount of residual shunt(5-10 microbubbles).Conclusion Patent foramen ovale closure can significantly alleviate the headache symptoms of patients with migraine caused by congenital foramen ovale.
作者
帕尔哈提·吐尔逊
叶海涛
柴宇燕
杨燕
比拉里·艾山
李秀芬
Paerhati·Tuerxun;YE Haitao;CHAI Yuyan;YANG Yan;Bilali·Aishan;LI Xiufen(Department of Cardiology,The Fourth Affiliated Hospital of Traditional Chinese Medicine,XinjiangMedical University,Urumqi,Xinjiang 830000,China)
出处
《新疆医学》
2019年第6期582-585,581,共5页
Xinjiang Medical Journal
