摘要
目的对国内外关于心理干预对胃肠道恶性肿瘤患者负性情绪及生活质量的影响进行系统性评价。方法对万方数据库、维普中文科技期刊全文数据库、中国知网、中国生物医学文献数据库、Europe PMC、Pubmed、EMbase、Web of Science和Cochrane Central等数据库2009年1月至今公开发表的关于心理干预对胃肠道恶性肿瘤患者负性情绪及生活质量的影响的报道进行检索并筛选,评价文献质量,并进行meta分析。结果本研究共提取9篇文献,观察组共398例、对照组共398例,共纳入受试者896例,均为高质量文献;护理后SAS、SDS、EORTC QLQ C30、SF 36评分报道均无显著异质性(P>0.05),meta分析显示,观察组护理后SAS评分显著降低(WMD=-20.63,95%CI为-34.82^-14.57,P<0.01),SDS评分显著降低(WMD=-7.89,95%CI为-10.02^-5.63,P<0.01),EORTC QLQ-C30评分显著提高(WMD=5.67,95%CI为2.18~7.12,P<0.01),SF-36评分显著提高(WMD=3.63,95%CI为0.97~5.88,P<0.01)。各项文献间均未发现明显的偏倚风险。结论心理干预能够显著减轻胃肠道恶性肿瘤患者焦虑、抑郁情绪,提升生活质量。
Objective To systematically evaluate the impact of psychological intervention on negative emotions and quality of life in patients with gastrointestinal malignant tumors at home and abroad.Methods Papers published in the databases of Wanfang,WIP Chinese Sci tech,China How Net,China Biomedical Literature Database,European PMC,Pubmed,EMbase and Web of science and Cochrane Central from January 2009 to now on the impact of psychologi cal intervention on negative emotions and quality of life of patients with gastrointestinal malignant tumors were retrieved and screened,and the quality of literature was evaluated to conduct a meta analysis.Results Nine literatures were extract ed and they were all with high quality.A total of 896 subjects were enrolled,including 398 in the observation group and 398 in the control group.There were no significant differences in the heterogeneity test of SAS,SDS,EORTC QLQ C30 and SF 36 scores after nursing(P>0.05 for all).Meta analysis showed that the SAS scores of the observation group were significantly decreased(WMD=-20.63,95%CI:-34.82--14.57,P<0.01),SDS scores decreased significantly(WMD=-7.89,95%CI:-10.02--5.63,P<0.01),EORTC QLQ-C30 scores increased significantly(WMD=5.67,95%CI:2.18-7.12,P<0.01),and SF-36 scores increased significantly(WMD=3.63,95%CI:0.97-5.88,P<0.01).No significant risk of bias was found among the literatures.Conclusion Psychological intervention can significantly reduce anxiety and depression in patients with gastrointestinal malignant tumors,and improve their quality of life.
作者
廖巧玲
李小麟
LIAO Qiao-ling;LI Xiao-lin(West China Hospital of Sichuan University,Chengdu 610041,China;Sichuan Mental Health Center/The Third Hospital of Mianyang)
出处
《华南预防医学》
2019年第5期428-431,485,共5页
South China Journal of Preventive Medicine
关键词
心理干预
恶性肿瘤
负性情绪
生活质量
Psychological intervention
Malignant tumor
Negative emotion
Quality of life
