摘要
目的探讨康复护理干预对膝骨关节炎患者关节功能的影响以及治疗效果。方法选取2016年7月-2018年7月青岛市市立医院骨科接诊的280例膝骨关节炎患者为研究对象,按照随机数表法将患者分为研究组和对照组,各140例,对照组在药物治疗的基础上采用常规护理干预,研究组在药物治疗的基础上采用康复护理干预,记录2组患者的治疗效果、膝关节Lysholm评分、视觉模拟评分、生活质量和白细胞介素-1(interleukin-1,IL-1)、白细胞介素-6(interleukin-6,IL-6)、环氧化酶-2(cyclooxygenase-2,COX-2)和基质金属蛋白酶-3(matrix metalloproteinase-3,MMP-3)水平。结果研究组总有效率为94.28%,显著高于对照组的71.43%,差异有统计学意义(P<0.05);干预后,2组患者膝关节Lysholm评分较干预前升高,视觉模拟评分较干预前降低,差异有统计学意义(P<0.05),且研究组膝关节Lysholm评分高于对照组,视觉模拟评分低于对照组,差异均有统计学意义(P<0.05);干预后,2组患者工作维度、躯体维度、情绪维度、症状维度和社交维度评分均较干预前升高,差异有统计学意义(P<0.05),且研究组各维度评分均高于对照组,差异有统计学意义(P<0.05);干预后,2组患者MMP-3、COX-2、IL-6和IL-1水平均较干预前降低,差异有统计学意义(P<0.05),且研究组各炎性指标水平均低于对照组,差异有统计学意义(P<0.05)。结论在使用药物治疗膝骨关节炎的基础上采取康复护理能够提高患者生活质量,降低炎性反应,减轻患者疼痛,提高膝关节功能,提高治疗效果。
Objective To explore the effect of rehabilitation nursing on joint function and the therapeutic effect of knee osteoarthritis patients.Methods A total of 280patients with knee osteoarthritis admitted by the Department of Orthopaedics,Qingdao Municipal Hospital from July 2016to July 2018were selected as the subjects,and randomly divided into two group.Each of 140cases in control group using the routine intervention on the basis of drug treatment,while study group was treated with rehabilitation nursing intervention on the basis of drug treatment.The therapeutic effect,Lysholm score,visual analogue score,quality of life and and interleukin-1(IL-1),interleukin-6(IL-6),cyclooxygenase-2(COX-2)and matrix metalloproteinase-3(MMP-3)levels of the two groups were recorded.Results The total effective rate of the study group was 94.28%,which was significantly higher than that of the control group(71.43%).The difference was statistically significant(P<0.05).After the intervention,the Lysholm score of the knee joint was increased and the visual analog score was decreased.The differences were statistically significant(P<0.05).The visual simulation score was lower than that of the control group,and the difference was statistically significant(P<0.05).After the intervention,the working dimension and body dimension of the two groups were observed.Emotional dimension,symptom dimension and social dimension score were all increased,and the differences were statistically significant(P<0.05),and the scores of each dimension of the study group were higher than the control group,and the difference was statistically significant(P<0.05).After the intervention,the levels of IL-1,IL-6,COX-2and MMP-3in the two groups were significantly lower(P<0.05),and the inflammatory markers in the study group were lower than in the control group(P<0.05).Conclusion The use of drugs to treat knee osteoarthritis combining with comprehensive rehabilitation intervention can improve the quality of life of patients,reduce inflammatory response,reduce pain,and improve knee function.
作者
胡光亮
徐迈
周伦
毛世刚
马振华
刘波
HU Guangliang;XU Mai;ZHOU Lun;MAO Shigang;MA Zhenhua;LIU Bo(Department of Orthopedics,Qingdao Municipal Hospital,Shandong Qingdao 266087,China)
出处
《新疆医科大学学报》
CAS
2019年第11期1497-1501,共5页
Journal of Xinjiang Medical University
基金
山东省重点研发计划项目(2017GSE19116)
关键词
康复护理
药物治疗
膝骨关节炎
关节功能
rehabilitation nursing
drug treatment
knee osteoarthritis
joint function
