摘要
目的建立液相色谱串联质谱法检测一次性纸杯中全氟辛酸、全氟辛烷磺酸向食品模拟物中的迁移量。方法待测样品经前处理后,通过C18色谱柱进行分离,以乙腈-水为流动相进行梯度洗脱、流速0.2 mL/min、柱温为30℃、进样量2μL,由三重四级杆质谱进行定性和定量分析。结果全氟辛酸和全氟辛烷磺酸在0.1~2.0 ng/mL范围内线性关系良好,相关系数均≥0.999;低、中、高3个添加水平的平均加标回收为81.27%~97.12%;相对标准偏差为2.9%~7.4%。应用建立的方法对一次性纸杯进行模拟迁移试验,初步得到了这2种物质在不同模拟状态下的迁移量。结论该方法选择性强、灵敏性和准确度高,适用于一次性纸杯中全氟辛酸和全氟辛烷磺酸的确证和定量分析。
Objective To determine the migration of perfluorooctanoic acid and perfluorooctanoic acid to food simulants in disposable paper cups by liquid chromatography tandem mass spectrometr y. Methods After pre-treatment, the samples were separated by C18 chromatographic column at the flow rate of 0.2 mL/min by gradient elution using acetonitrile and water as mobile phase. The temperature of the column oven was maintained at 30 ℃, the injection volume was 2 μL, and the triple quadrupole mass spectrometry was performed for qualitative and quantitative analysis. Results Perfluorooctanoic acid and perfluorooctanoic acid had a good linear relationship within the range of 0.1-2.0 ng/mL, and the correlation coefficients were ≥0.999. The recoveries at 3 spiked levels were 81.27%-97.12%, with the relative standard deviations of 2.9%-7.4%.The simulated migration test was carried out on the disposable paper cups by the established method, and the migration of the two substances under different simulation conditions was preliminarily obtained. Conclusion The method has high selectivity, sensitivity and accuracy, and is suitable for the confirmation and quantitative analysis of perfluorooctanoic acid and perfluorooctanoic acid in disposable paper cups.
作者
刘征辉
魏静娜
赵琳琳
赵云平
薛天凯
黄迪
王亚旭
周茜
LIU Zheng-Hui;WEI Jing-Na;ZHAO Lin-Lin;ZHAO Yun-Ping;XUE Tian-Kai;HUANG Di;WANG Ya-Xu;ZHOU Qian(Tianjin Agricultural Quality Standards and Testing Technology Research Institute,Tianjin 300081,China;Tianjin High-standard Quality Testing Lab.,Tianjin 300081,China;Agricultural University of Hebei Province,Baoding 071000,China)
出处
《食品安全质量检测学报》
CAS
2019年第20期6968-6974,共7页
Journal of Food Safety and Quality
基金
河北省重点研发计划项目(16275504D)
天津农科院院长基金项目(17004)~~
关键词
全氟辛酸
全氟辛烷磺酸
一次性纸杯
食物模拟物
方法学
迁移量
定量分析
perfluorooctanoic acid
perfluorooctane sulfonic acid
disposable paper cup
food simulants
methodology
migration
quantitative analysis
