摘要
目的研究钴-60射线辐照对白术药材中有效成分的影响。方法选不同批号白术进行钴-60射线辐照,观察其对有效成分的影响。结果随辐照剂量升高,药材含菌量减少;白术内酯Ⅰ、Ⅱ、Ⅲ及苍术酮在0.012~0.213、0.012~0.210、0.014~0.246、0.091~1.874μg线性良好;辐照前后白术内酯Ⅰ、Ⅱ、Ⅲ的含量比较差异无统计学意义(P>0.05),但辐照前后苍术酮差异有统计学意义(P<0.05)。结论钴-60射线辐照剂量不超过5 kGy时,4种成分变化无明显性,为白术辐照灭菌方式提供参考依据。
Objective To study the influence of Cobalt-60 irradiation in four active ingredients of Atractylodes macrocephala.Methods The different batches of Atractylodes macrocephala were selected;after the Cobalt-60 irradiation,the atractylenolide Ⅰ,Ⅱ,Ⅲ and atractylon ingredients were analyzed.Results With the higher irradiation doses,the amount of the drug bacteria was remarkably decreased;the atractylenolide Ⅰ,atractylenolide Ⅱ,atractylenolide Ⅲ and atractylon ingredients were 0.012~0.213,0.012~0.210,0.014~0.246 and 0.091~1.874μg,respectively,indicating the fine linear relationships;before and after irradiation,the atractylenolide I and atractylenolide II ingredients were not significantly different(P>0.05);before and after irradiation,the atractylon ingredients were significantly different(P<0.05).Conclusion When the irradiation exceeds 5 kGy,four ingredients of Atractylodes macrocephala are not significantly different.It provides the basis on the irradiation sterilization modes of atractylodes macrocephala.
作者
吕海涛
LV Haitao(The First Subsidiary Hospital of the GuiYang Traditional Medical Academy,Guiyang,Guizhou 550001,China)
出处
《大医生》
2019年第7期74-75,共2页
Doctor
关键词
有效成分
白术
钴-60射线辐照
中药材
active ingredients
atractylodes macrocephala herbs
Cobalt-60 irradiation
traditional chinese medicines
