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血清和肽素对急性心肌梗死的早期诊断和预后评估的价值

Value of Copeptin in Early Diagnosis and Prognosis Evaluation of Acute Myocardial Infarction
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摘要 目的探讨血清和肽素对急性心肌梗死的早期诊断和预后评估的价值。方法选取2016年2月至2017年2月黑龙江省医院南岗分院收治的80例因持续胸痛3 h内疑似急性心肌梗死的患者作为观察组研究对象,选取同期健康体检者80例作为对照组,测定不同时间段肌钙蛋白I水平、血清和肽素水平,随访观察组1年,记录心血管事件发生情况。结果观察组胸痛发作3、6、12、24 h等时间段和肽素、肌钙蛋白I水平均显著高于对照组(P<0.05);胸痛发作24 h和肽素水平比较明显高于未发生心血管不良事件时(P<0.05)。结论在急性心肌梗死诊断中进行血清和肽素检测具有良好的早期诊断价值,且持续检测可评估患者预后,应用价值较高。 Objective To investigate the value of copeptin in the early diagnosis and prognosis evaluation of acute myocardial infarction.Methods From February 2016 to February 2017,80 patients suspected of acute myocardial infarction within three hours due to persistent chest pain were selected as the study group,and 80 healthy people as the control group.The levels of troponin I,copeptin were measured in different time periods.The observation group was followed up for 1 year to record the cardiovascular events.Results The levels of copeptin and troponin I in the observation group were significantly higher than those in the control group at 3,6,12 and 24 h after the onset of chest pain(P<0.05).The level of copeptin in patients with chest pain 24 h was significantly higher than that without adverse cardiovascular events(P<0.05).Conclusion Copeptin detection in the diagnosis of acute myocardial infarction has a good early diagnostic value,and continuous detection can evaluate the prognosis of patients with high value.
作者 杨艳 杨静 宋宇 倪欣 姚兰英 YANG Yan;YANG Jing;SONG Yu;NI Xin;YAO Lanying(Nangang Branch,Heilongjiang Provincial Hospital,Harbin,Heilongjiang 150000,China;Digestive Endoscopy Room,Nangang branch,Heilongjiang Provincial Hospital,Harbin,Heilongjiang 150000,China;Digestive Department,Nangang Branch of Heilongjiang Provincial Hospital,Harbin,Heilongjiang 150000,China)
出处 《大医生》 2019年第4期96-97,共2页 Doctor
基金 课题项目名称:血清和肽素对急性心肌梗死早期诊断及预后的评估,课题项目:黑龙江省卫生计生委科研课题(编号:2016-500)。
关键词 血清和肽素 急性心肌梗死 早期诊断 serum and peptide acute myocardial infarction early diagnosis
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