期刊文献+

地佐辛复合丙泊酚静脉麻醉在无痛胃镜检查中的应用效果及不良反应研究 被引量:8

Application Effect and Adverse Reaction of Dizosin Combined with Propofol Intravenous Anesthesia in Painless Gastroscopy
下载PDF
导出
摘要 目的 探索地佐辛复合丙泊酚静脉麻醉在无痛胃镜检查中的应用效果及不良反应。方法 方便选取2018年1-12月期间该院实施无痛胃镜检查60例患者(实施奇偶数法分组模式),对照组的30例患者进行芬太尼麻醉,观察组的30例患者进行地佐辛复合丙泊酚静脉麻醉。结果 观察组患者检查中VAS评分(0.53±0.19)分、检查中Ramsay镇静评分(3.99±0.27)分、拔除胃镜后立即VAS评分(1.95±0.56)分、拔除胃镜后立即Ramsay镇静评分(2.26±0.57)分、PaO2(96.88±9.63)mmHg、睁眼时间(5.65±1.86)min、睫毛反射消失时间(2.84±1.39)min、麻醉起效时间(4.92±1.37)min、丙泊酚用量(124.58±16.86)mg、不良反应(6.67%)均优于对照组,差异有统计学意义(t=1.529、1.188、2.432、2.137、51.398、5.623、4.153、4.266、56.325,χ^2=11.624,P<0.05),同时观察组各时间段的MAP、HR稳定情况优于对照组,差异有统计学意义(P<0.05)。结论 在实施无痛胃镜检查时,运用地佐辛复合丙泊酚静脉麻醉效果显著,且安全性更高。 Objective To explore the application effect and adverse reactions of dextrozine combined with propofol intravenous anesthesia in painless gastroscopy.Methods From January to December 2018,convenient selected 60 patients with painless gastroscopy were performed in the hospital(the odd-even group method was implemented),and 30 patients in the control group underwent fentanyl anesthesia.30 patients underwent intravenous anesthesia with dextrozine combined with propofol.Results In the observation group,the VAS score(0.53±0.19)points,the Ramsay sedation score(3.99±0.27)points,the VAS score(1.95±0.56)points after removal of the gastroscope,and the Ramsay sedation score(2.26±0.57)points immediately after removal of the gastroscope,PaO2(96.88±9.63)mmHg,blink time(5.65±1.86)min,eyelash reflex disappearance time(2.84±1.39)min,anesthesia onset time(4.92±1.37)min,propofol dosage(124.58±16.86)mg and adverse reactions(6.67%)were superior to the control group,the difference was statistically significant(t=1.529,1.188,2.432,2.137,51.398,5.623,4.153,4.266,56.325,χ^2=11.624,P<0.05),while observing the MAP of each time period of the group,the stability of HR was better than that of the control group,the difference was statistically significant(P<0.05).Conclusion In the implementation of painless gastroscopy,intravenous anesthesia with dizocine combined with propofol is effective and safe.
作者 王香 WANG Xiang(Department of Anesthesiology,Yixing People's Hospital,Yixing,Jiangsu Province,214200 China)
出处 《中外医疗》 2019年第29期91-93,共3页 China & Foreign Medical Treatment
关键词 地佐辛复合丙泊酚 静脉麻醉 无痛胃镜 不良反应 Dextrozine combined with propofol Intravenous anesthesia Painless gastroscopy Adverse reactions
  • 相关文献

参考文献14

二级参考文献80

  • 1庄心良,曾因明,陈伯銮.现代麻醉学.第3版.北京:人民卫生出版社,2008:1301.
  • 2曾因明,邓小明,主译.米勒麻醉学[M].第6版.北京:北京大学医学出版社,2006:410-411.
  • 3Gharagozlou P, Hashemi E, Delorey T M, et al.Pharmacological profiles of opioid ligands at kappa opioid receptors[J].BMC Pharmacol, 2006, 6(1):3.
  • 4Picher M J.Discriminative stimulus effects of the mixed-opioid agonist/ antagonist dezocine: cross-substitution by mu and delta opioid agonists[J].J Pharmacol Exp Ther, 1997:283 ( 3 ) : 1009-1017.
  • 5I Herrera-Peeo I, Wix-Ramos:R, Domfnguez-Gadea L, et al.Changes in cerebral perfusion induced by etomidate in patients with temporal lobe epilepsy[J].Rev Neurol, 2009, 49 ( 11 ) : 561-565.
  • 6Aisenberg J. Gastrointestinal endoscopy in patients taking novel oral anticoagulants[J]. Gastroenterol Hepatol (N Y), 2014,10(2):117-119.
  • 7Effenberger M1, Steinle H, Offner FA, et al. Holes in gastric mucosa in upper gastrointestinal endoscopy [J]. Eur J Gastroenterol Hepatol,2014,26(6):676-678.
  • 8Tronnier VM, Raschc D. Neuroablative procedures in pain therapy[J].Schmerz, 2009, 23(5):531-541.
  • 9Zahn PK, Sabatowski R, Schug SA, et al. Paracetamol for perioperative analgesia old substance new insights [J]. Anaesthesist,2010,59(10):940-952.
  • 10Sitilci AT, Ozyuvacl E, Alkan Z, et al. The effect of perioperative infused dexmedetomidine on postoperative analgesic consumption in mastoidectomy operations[J]. Agri, 2010,22(3):109-116.

共引文献156

同被引文献82

引证文献8

二级引证文献15

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部