摘要
心力衰竭是各种心血管疾病的终末阶段,而病理性心肌肥厚是心力衰竭进程的一个关键时期.研究发现,抵抗素与病理性心肌肥厚的进展密切相关,其内在涉及多条信号传导通路.详细了解其相关机制,有助于寻找新的治疗靶点,延缓病理性心肌肥厚的进展.
Heart failure is the terminal stage of various cardiovascular diseases and pathological cardiac hypertrophy is a critical period of heart failure.Resistin is closely related to the progression of pathological cardiac hypertrophy and the underlying involving multiple signaling pathways.Fully understanding of its mechanisms will be helpful in finding new therapeutic targets and delaying the progression of pathological cardiac hypertrophy.
作者
高敏
邓勇志
闫晓亮
GAO Min;DENG Yong-zhi;YAN Xiao-liang(Department of Cardiovascular Surgery,The Affiliated Cardiovascular Hospital of Shanxi Medical University and Shanxi Cardiovascular Hospital(Institute),Taiyuan 030024,China)
出处
《中国心血管病研究》
CAS
2019年第11期1042-1046,共5页
Chinese Journal of Cardiovascular Research
关键词
抵抗素
病理性心肌肥厚
Resistin
Pathological myocardial hypertrophy