摘要
目的通过对秦皇岛地区备孕期妇女甲功三项(促甲状腺激素TSH、游离甲状腺激素FT4、游离三碘甲腺原氨酸FT3)的检测,分析甲状腺疾病在育龄期妇女的发病率,同时积极治疗甲状腺疾病,防止不良妊娠结局的发生。方法采集2018年1月-12月行孕前体检的备孕期妇女420例静脉血,采用化学发光法检测血中TSH、FT4、FT3,对结果进行统计分析。结果秦皇岛地区备孕期妇女甲功异常发生率为13.6%,其中甲减1.2%,亚临床甲减11%,甲亢0.7%,亚临床甲亢0.7%;既往有胎停育、死胎等不良孕史组甲功异常的发生率较无不良孕产史组明显升高,差异有统计学意义(P<0.05)。
Objective:To investigate the incidence of thyroid diseases in prepregnancy women in Qinhuangdao through the detection of thyroid hormone(Thyroid stimulating hormone,free thyroid hormone,free triiodothyroid acid),at the same time,active treatment of thyroid disease,to prevent adverse pregnancy outcome.Methods:420 cases were collected from prepregnant women who underwent physical examination from January to December,2018,the levels of TSH,FT4,FT3 were detected by chemiluminescence method in venous blood,and the results were statistically analyzed.Results:The incidence of abnormal thyroid function in prepregnant women in Qinhuangdao was 13.6%,including 1.2%hypothyroidism,11%subclinical hypothyroidism,0.7%hyperthyroidism and 0.7%subclinical hyperthyroidism.The incidence of abnormal thyroid function in the group with a history of adverse pregnancy,such as abortion and stillbirth,was significantly higher than that in the group without a history of adverse pregnancy(P<0.05).
作者
蒋向荣
周书梅
周柳
侯凌云
JIANG Xiang-rong;ZHOU Shu-mei;ZHOU Liu;HOU Ling-yun(Qinhuangdao Maternal and Child Health Care Hospital,Qinhuangdao,066000;Qinglong Maternal and Child Health Care Hospital,Qinhuangdao,066500)
出处
《中国优生与遗传杂志》
2019年第10期1207-1208,1229,共3页
Chinese Journal of Birth Health & Heredity
关键词
秦皇岛地区
备孕期
甲状腺功能
Qinhuangdao area
Prepregnancy
Thyroid function
