摘要
目的通过对腮腺肿瘤的能谱曲线斜率(SACS)、曲线下面积(AUC)、标准化碘基值(NIC)、碘浓度差(ICD)的比较,分析能谱定量参数值在腮腺肿瘤定性诊断中的应用价值。方法应用能谱CT对92例腮腺肿瘤患者进行动脉期(AP)、静脉期(VP)增强扫描。依据病理结果分为多形性腺瘤组(A组)、沃辛瘤组(B组)、基底细胞腺瘤组(C组)、恶性肿瘤组(D组)。测量并计算双期扫描中肿瘤的SACS、AUC、NIC及ICD。多组定量资料比较采用单因素方差分析,P<0.05为差异具有统计学意义。结果A组SACSAP、AUCAP及NICAP均低于其余各组,C组SACSVP、AUCVP均高于其余各组,D组NICAP、NICVP高于其他各组,B组ICD差值为正值。除B组和C组间SACSAP、AUCAP的差异以及C组和D组间SACSVP、AUCVP的差异以及A组和C组间ICD的差异无统计学意义外,其余各组之间的差异均具有统计学意义(P<0.05)。A组和B组、C组和D组间NICAP的差异以及A组和C组、A组和D组、B组和C组NICVP的差异具有统计学意义(P=0.005、0.025、0.002、0.038、0.049)。结论不同病理类型的腮腺肿瘤能谱CT定量参数值存在差异,利用能谱CT多参数成像有助于腮腺肿瘤的定性诊断。
Objective This study aimed to investigate the value of normalized iodine concentration(NIC),spectral attenuation curve slope(SACS),area under curve(AUC),and iodine concentration difference(ICD)generated from spectral CT in the assessment of parotid gland tumors.Methods Ninety-two patients with pathologically confirmed parotid gland tumors underwent arterial phase-and venous phase-enhanced CT in spectral CT.The patients were divided into the pleomorphic adenoma group(group A),Warthin tumor group(group B),basal cell tumor group(group C),and malignant tumor group(group D).The SACS,AUC,NIC,ICD were measured and analyzed.Statistical analyses were performed by one-way ANOVA,and statistical significance was set at P<0.05.Results SACSAP,AUCAP,and NICAP in group A were lower than those in other groups;SACSVP and AUCVP in group C were higher than those in other groups;NICAP and NICVP in group D were higher than those in other groups;and ICD in group B was a positive number.The difference in SACSAP and AUCAP in groups B and C,SACSVP and AUCVP in groups C and D,and ICD in groups A and C were not statistically significant.By contrast,the difference between the other groups was statistically significant(P<0.05).The difference in NICAP between groups A and B and groups C and D and the difference in NICVP between groups A and C,groups A and D,and groups B and C were statistically significant(P=0.005,0.025,0.002,0.038,and 0.049,respectively).Conclusion Multi-quantitative parameters from spectral CT might be helpful in differentiating various types of parotid gland tumors.
作者
苏蕾
谢晨露
孙强
高剑波
Su Lei;Xie Chenlu;Sun Qiang;Gao Jianbo(Dept.of Radiology,The First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China;Dept.of Stomatology,The First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China)
出处
《华西口腔医学杂志》
CAS
CSCD
北大核心
2019年第6期631-635,共5页
West China Journal of Stomatology
基金
国家自然科学基金(81402231)
河南省科技厅科技攻关项目(172102310262)~~
关键词
腮腺肿瘤
体层摄影术
能谱成像
碘基值
parotid gland tumor
tomography
spectral imaging
iodine concentration
