摘要
目的分析老年体外循环(CPB)心脏手术患者术后认知功能障碍(POCD)的相关因素。方法选取2017年3月~2019年3月在解放军西部战区总医院心脏外科行CPB下心脏瓣膜手术的206例患者作为研究对象。根据是否发生POCD,将患者分为POCD组(58例)和非POCD组(148例),并对POCD的相关因素进行分析。结果POCD组患者年龄大于非COPD组,受教育年限、CPB时间、主动脉阻断时间、术后机械通气时间、术后住ICU时间均长于非POCD组,差异有统计学意义(P<0.05)。年龄、受教育年限、CPB时间、主动脉阻断时间是老年CPB下心脏手术患者POCD发生的影响因素(P<0.05)。结论老年CPB下心脏手术患者POCD的发生与年龄、受教育年限、CPB时间和主动脉阻断时间有关。临床医生应给予高度的重视,采取有针对性的预防措施,降低POCD的发生风险。
Objective To explore the related factors of postoperative cognitive dysfunction(POCD)in elderly patients undergoing cardiac surgery under cardiopulmonary bypass(CPB).Methods Two hundred and six patients undergoing cardiac valve surgery under CPB in the Cardiac Surgery Department of Western Military General Hospital from March 2017 to March 2019 were enrolled.The patients were divided into POCD group(58 cases)and non-POCD group(148 cases),according to whether they had POCD or not,while the related factors of POCD were analyzed.Results Patients in the POCD group were older than that in the non-POCD group,while the education years,CPB time,aortic occlusion time,postoperative mechanical ventilation time,postoperative ICU hospitalization time of patients in POCD group were significantly longer than those in non-POCD group,and the differences were statistically significant(P<0.05).The related factors of the incidence of POCD in elderly patients undergoing cardiac surgery under CPB were age,the education years,CPB time and aortic occlusion time(P<0.05).Conclusion The occurrence of POCD in elderly patients undergoing cardiac surgery under CPB is related to the age,education years,CPB time and aortic occlusion time.Clinical doctors should pay a high degree of attention and take targeted preventive measures to reduce the risk of POCD.
作者
岳琴
邬晓臣
王舰
丁盛
辛梅
张近宝
YUE Qin;WU Xiaochen;WANG Jian;DING Sheng;XIN Mei;ZHANG Jinbao(Department of Cardiovascular Surgery,Western Military General Hospital,Sichuan Province,Chengdu 610083,China)
出处
《中国医药导报》
CAS
2019年第29期65-67,共3页
China Medical Herald
基金
国家自然科学基金资助项目（81701115）
关键词
老年
体外循环
心脏手术
术后认知功能障碍
相关因素
Elderly
Cardiopulmonary bypass
Cardiac surgery
Postoperative cognitive dysfunction
Related factors
