摘要
目的探究生血宝合剂对妊娠期贫血的疗效。方法选取本院120例妊娠期贫血患者为研究对象,采用随机数字表法分为单独使用右旋糖酐铁片组(对照组,n=60)和单独使用生血宝合剂组(观察组,n=60)。对比两组临床疗效和治疗期间不良反应(便秘、恶心呕吐、上腹部不适)的发生情况,对比两组患者治疗前、治疗2周后的血红蛋白(Hb)指标、红细胞(RBC)、血细胞比容(Hct)差异。结果治疗2周后,观察组和对照组Hb均较治疗前升高,同组治疗前后比较差异有统计学意义(观察组t=9.132,P<0.05;对照组t=5.012,P<0.05);观察组和对照组RBC提升的总有效率分别为93.3%、75.0%,两组比较差异具有统计学意义(Z=5.185,P<0.05);两组Hct提升的总有效率分别为95.0%、80.0%,两组比较差异具有统计学意义(Z=3.652,P<0.05);在不良反应方面,观察组和对照组的总发生率分别为8.3%、43.3%,观察组的总发生率显著低于对照组,两组差异具有统计学意义(P<0.05)。结论生血宝合剂对妊娠期贫血疗效较好,不仅能缓解患者贫血症状,还能降低治疗不良反应,值得临床推广应用。
Objective To explore the effect of Shengxuebao Mixture on anemia during pregnancy. Methods 120 patients with gestational anemia in our hospital were selected as the research subjects. The patients were divided into two groups: iron dextran tablet group(control group, n=60)and Shengxuebao mixture group(observation group, n=60). The clinical efficacy and adverse reactions(constipation, nausea and vomiting, upper abdominal discomfort) were recorded and compared between the two groups. The difference of hemoglobin(Hb), erythrocyte(RBC) and hematocrit(Hct) before and after treatment were compared between the two groups. Results After 2 weeks of treatment, Hb in the observation group and the control group increased compared with that before treatment, and there was significant difference between the two groups before and after treatment(observation group t=9.132, P<0.05;control group t=5.012, P<0.05). The total effective rate of RBC in the observation group and the control group was 93.3% and 75.0%, respectively, with significant difference between the two groups(Z=5.185, P<0.05). The total effective rate of Hct in the two groups was 93.3% and 75.0%, respectively. The rates were 95.0% and 80.0% respectively. There was significant difference between the two groups(Z=3.652, P<0.05). In terms of adverse reactions, the total incidence of observation group and control group was 8.3% and 43.3%, respectively. The total incidence of observation group was significantly lower than that of control group, and the difference between the two groups was significant(P<0.05). Conclusion Shengxuebao Mixture has a good effect on anemia during pregnancy. It not only alleviates the symptoms of anemia, but also reduces the adverse reactions of treatment. It is worthy of clinical application.
作者
刘俊
王玉
李月芬
Liu Jun;Wang Yu;Li Yuefen(Department of Obstetrics,Pingxiang Maternal and Child Health Hospital,Pingxiang,Jiangxi,337000,China)
出处
《当代医学》
2019年第33期94-96,共3页
Contemporary Medicine
关键词
妊娠期贫血
生血宝合剂
疗效
观察
Gestational anemia
Shengxuebao Mixture
Curative effect
Observation
