摘要
目的探讨对接受自体树突状细胞(DC)联合干扰素治疗的慢性乙型肝炎(CHB)患者实施针对性护理干预的效果。方法将92例研究对象随机分成观察组(46例)与对照组(46例),两组均实施自体DC联合干扰素治疗,期间给予对照组常规护理,给予观察组针对性护理干预,观察两组干预效果。结果护理后两组血丙氨酸转氨酶(ALT)、乙肝病毒脱氧核糖核酸(HBV DNA)指标均较护理前降低,但观察组降幅较对照组显著(P<0.05);观察组遵医嘱率为91.30%,显著高于对照组67.39%的遵医嘱率,观察组并发症发生率为4.35%,显著低于对照组17.39%的发生率,差异均有统计学意义(P<0.05)。结论将针对性护理干预应用到CHB行自体DC联合干扰素治疗期间,可取得显著干预效果,值得推广。
Objective To explore effect of targeted nursing intervention on chronic hepatitis B(CHB) patients treated with autologous dendritic cells(DC) combined with interferon. Methods Divide 92 cases research objects into observation group(46 cases) and control group(46 cases) randomly. Both groups were treated with autologous DC combined with interferon. During the period, control group was treated with routine nursing care, and observation group with targeted nursing intervention. Observe intervention effect of two groups. Results After nursing, blood alanine aminotransferase(ALT) and hepatitis B virus deoxyribonucleic acid(HBV DNA) of two groups was lower than before, but decrease of observation group was more significant than control group(P< 0.05);compliance rate of observation group was 91.30%, significantly higher than control group(67.39%), and complication incidence of observation group was 4.35%, significantly lower than control group(17.39%), difference showed statistical significance(P<0.05). Conclusion Targeted nursing intervention can achieve significant intervention effect in treatment of CHB with autologous DC combined with interferon, which is worthy of promotion.
作者
陈红
CHEN Hong(Qujing City the First People's Hospital,Qujing,Yunnan,655000)
出处
《智慧健康》
2019年第30期142-143,共2页
Smart Healthcare
关键词
针对性护理干预
自体DC
干扰素
慢性乙型肝炎
Targeted nursing intervention
Autologous DC
Interferon
Chronic hepatitis B
