摘要
目的了解甘肃部分地区城乡居民尿碘水平及其相关影响因素,为城乡居民科学摄碘提供参考依据。方法选取参加甲状腺疾病和碘营养状况全国调查项目的甘肃地区甲状腺功能正常人群作为调查对象,进行问卷调查,测量身高、体重、腰围,采集1次尿样,检测尿碘含量。根据不同性别、地区、年龄、体重、腰围、食盐摄入量等将调查对象分组,比较不同组间尿碘水平的差异,多重线性回归分析尿碘水平的影响因素。结果共纳入调查对象1964名,其中男性1099人,女性865人,年龄为(41.23±14.75)岁。城乡居民尿碘中位数(四分位数间距)为225.60(158.80,311.58)μg/L;其中,农村居民尿碘水平显著高于城市居民[μg/L:249.80(180.58,336.88)比206.25(148.03,280.33),Z=-8.015,P<0.05];男性尿碘水平与女性相近[μg/L:222.40(161.60,298.90)比230.60(158.00,326.40),P>0.05]。农村居民尿碘<100μg/L构成比低于城市(5.14%比8.27%,χ^2=7.45,P<0.05),农村居民尿碘≥300μg/L构成比高于城市(34.93%比21.51%,χ^2=43.87,P<0.05);男性尿碘≥300μg/L组的构成比低于女性(24.57%比31.21%,χ^2=10.73,P<0.05)。多重线性回归分析显示,居住于农村地区,年龄,中、重度食盐摄入量,学生群体,体重是影响尿碘的独立因素(β=0.074、-0.001、0.059、0.034、0.096、-0.003,P均<0.05)。随着年龄、体重的增加,尿碘水平逐渐降低(P均<0.05)。结论现阶段甘肃省部分城乡居民碘营养水平总体处于超过适宜量水平,农村居民尿碘水平比城市居民高,今后在防控工作上应密切关注居民的居住地区、食盐摄入量、体重等影响因素。
Objective To analyze the urinary iodine status of urban and rural residents in some areas of Gansu Province and its related influencing factors,and to provide certain references for scientific iodine intake of urban and rural residents in Gansu Province.Methods Subjects in Gansu Province with normal thyroid function were recruited in the investigation of thyroid diseases and iodine nutritional status,conducted a questionnaire survey and measured height,weight,waist circumference,collected 1 urine sample,and tested their urinary iodine levels.The urinary iodine levels of different groups were compared based on different gender,region,age,body weight,the waist,and salt intaking.The affecting factors of urinary iodine levels were analyzed by multiple linear regression models.Results Totally 1964 subjects were recruited,including 1099 males,and 865 females.The age was(41.23±14.75)years old.The median urinary iodine of the selected group was 225.60(158.80,311.58)μg/L.The urinary iodine level of rural residents was significantly higher than that of urban residents[μg/L:249.80(180.58,336.88)vs 206.25(148.03,280.33),Z=-8.015,P<0.05],and there was no significant difference between the urinary iodine levels of male and female[μg/L:222.40(161.60,298.90)vs 230.60(158.00,326.40),P>0.05].The composition ratio of<100μg/L group in rural areas was lower than that in urban areas(5.14%vs 8.27%,χ^2=7.45,P<0.05),and the composition ratio of≥300μg/L group was higher than that in urban areas(34.93%vs 21.51%,χ^2=43.87,P<0.05).The composition ratio of≥300μg/L group in male was lower than that in female(24.57%vs 31.21%,χ^2=10.73,P<0.05).The multiple linear regression analysis showed that lived in rural areas,age,moderate and severe salt intaking,student,and weight were independently correlated with urinary iodine levels(β=0.074,-0.001,0.059,0.034,0.096,-0.003,P<0.05).And the urinary iodine levels were decreased with age and weight increased(P<0.05).Conclusions At present,the iodine nutrition level of urban and rural residents in some areas of Gansu Province is generally over the adequate level.The urinary iodine level of rural residents is higher than that of urban residents.In the future,we should pay attention to the impact of different living areas,salt intaking and body weight on urinary iodine levels to prevent thyroid diseases.
作者
高洁
刘靖芳
汤旭磊
傅松波
马丽华
焦彩虹
孙蔚明
牛滢
井高静
牛强龙
赵楠
李玉娟
乌丹
宋佩
郭惠萍
杨芳
滕卫平
单忠艳
Gao Jie;Liu Jingfang;Tang Xulei;Fu Songbo;Ma Lihua;Jiao Caihong;Sun Weiming;Niu Ying;Jing Gaojing;Niu Qianglong;Zhao Nan;Li Yujuan;Wu Dan;Song Pei;Guo Huiping;Yang Fang;Teng Weiping;Shan Zhongyan(Department of Endocrinology,the First Hospital of Lanzhou University,Lanzhou 730000,China;the First People's Hospital of Longnan,Longnan 746000,China;Department of Endocrinology,the First Affiliated Hospital of China Medical University,Shenyang 101100,China)
出处
《中华地方病学杂志》
CAS
CSCD
北大核心
2019年第11期898-902,共5页
Chinese Journal of Endemiology
基金
公益性行业科研专项项目(201402005)。
关键词
尿
碘
城市
农村
碘营养状况
影响因素
Urine
Iodine
Urban
Rural
Iodine status
Affecting factors