摘要
以2,2'-联吡啶-3,3'-二甲酰肼为原料,经过成环反应制备中间体2,2'-联吡啶-3,3'-二(4-氨基-1,2,4-三氮唑-3-硫醇),再经过醚化反应得到5个2,2'-联吡啶-3,3'-二(4-氨基-1,2,4-三氮唑-3-硫醚)系列目标化合物,其结构通过1HNMR、13CNMR、MS、IR、元素分析以及单晶X-射线衍射等技术进行表征。结果表明,中间体及目标化合物均存在转阻异构体,硫醚化合物的分子结构形状受末端基团影响较大,中间体可与对称四甲基六元瓜环形成1∶2的主-客体超分子配合物。
A series of novel 2,2'-bipyridine-3,3'-bis(4-amino-1,2,4-triazole-3-thioether)and the intermediate of 2,2'-bipyridine-3,3'-bis(4-amino-1,2,4-triazole-3-thiol)were synthesized from the starting reagent of 2,2'-bipyridine-3,3'-diformylhydrazine.The structures of the compounds were conformed by 1HNMR,13CNMR,MS,IR,elemental analysis,and single-crystal Xray diffraction analysis.The result of single-crystal X-ray diffraction revealed that both the intermediate and target compounds have chiral atropisomerics.The total molecular shape of thiother is greatly affected by their terminal groups.Two intermediates were outersided the two ports of TMeQ[6]then self-assembly formed 1∶2 host-guest complex in aqueous solution of dilute hydrochloric acid.
作者
易君明
郑玉国
陈明华
YI Jun-ming;ZHENG Yuguo;CHEN Ming-hua(Key Laboratory of Chemical Synthesis and Environmental Pollution Control-remediation Technology,School of Biology and Chemistry,Xingyi Normal University for Nationalities,Xingyi 562409,China))
出处
《化学试剂》
CAS
北大核心
2019年第11期1189-1196,共8页
Chemical Reagents
基金
贵州省自然科学基金项目(黔科合[2016]7038、LH[2014]7411号)
贵州省教育厅项目(2016年教改第163号、黔教合KV[2015]393号)
