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头孢哌酮-舒巴坦钠对糖尿病伴泌尿系统感染患者的临床疗效及其对尿液中致病菌清除的影响 被引量:1

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摘要 目的:评价头孢哌酮-舒巴坦钠对糖尿病伴泌尿系统感染患者的临床疗效及其对尿液中致病菌清除的影响。方法:选取2017年1月-2019年1月期间收治的糖尿病伴泌尿系统感染患者60例资料,按治疗方法的不同将其分为A组和B组(每组30例);A组患者给予左氧氟沙星治疗,B组患者给予头孢哌酮-舒巴坦钠治疗,比较两组患者治疗后的总有效率、治疗期间不良反应发生率及尿液标本中致病菌(肠球菌属、大肠埃希菌、凝固酶阴性葡萄球菌)的检出值和高倍镜下白细胞个数值的差异,以及治疗前后血糖指标即空腹血糖(GLU)和餐后2 h血糖(PBG)水平测得值的变化情况。结果:B组患者治疗后的总有效率高于A组(P<0.05),治疗期间不良反应发生率低于A组(P<0.05);两组患者治疗前的GLU、PBG水平测得值经组间比较其差异均无统计学意义(P>0.05),治疗后的GLU、PBG水平测得值均低于治疗前(P<0.05);B组患者治疗后的GLU、PBG均低于A组(P<0.05),尿液标本中致病菌(肠球菌属、大肠埃希菌、凝固酶阴性葡萄球菌)的检出值和白细胞计数测得值均低于A组(P<0.05)。结论:采用头孢哌酮-舒巴坦钠治疗糖尿病伴泌尿系统感染患者的疗效优于左氧氟沙星,有效改善了其血糖值,提高了对致病菌的清除率。
机构地区 峡江县人民医院
出处 《抗感染药学》 2019年第10期1779-1781,1840,共4页 Anti-infection Pharmacy
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  • 1Sui R, Zhang L. Risk factors of stroke - associated pneumonia in Chi- nese patients [ J ]. Neurological Research, 2011, 33 ( 5 ) : 508 -513.
  • 2Zhang X, Wang F. Risk factors for developing pneumonia in patients with diabetes mellitus following acute ischaemic stroke [ J]. Journal of International Medical Research, 2012, 40 (5): 1860-1865.
  • 3Majumder MI,Ahmed T’Hossain D. Bacteriology and an-tibiotic sensitivity patterns of urinary tract infections in atertiary hospital in Bangladesh [J], MMJ,2014,23(1) :99-104.
  • 4Park YS,Bae IK,Kim J. Risk factors and molecular epi-demiology of community-onset extended-spectrum P-lac-tamase -producing Escherichia coli bacteremia [J]. YonseiMedical Journal,2014,55(2) :467-475.
  • 5戴自英,刘裕民.实用抗菌药学[M].上海:上海科学技术出版社,1998,131-140.
  • 6Garraffo A,Marguet C,Checoury A,et al. Urinary tractinfections in hospital pediatrics: many previous antibio-therapy and antibiotics resistance,including fluoro-quinolones [J]. Med Mai Infect,2014,44(2) :63-68.
  • 7Kugathasan R,Wootton M,Howe R. Cycloserine as analternative urinary tract infection therapy: susceptibilitiesof 500 urinary pathogens to standard and alternativetherapy antimicrobials [J]. Eur J Clin Microbiol InfectDis,2014,33(7):1169-1172.
  • 8Rogers BA, Ingram PR, Runnegar N,et al. Community -onset Escherichia coli infection resistant to expanded -spectrum cephalosporins in low-prevalence countries [J].Antimicrob Agents Chemotherherapy,2014,58(4):2126-2234.
  • 9Chan MC’Chiu SK, Hsueh PR. Risk factors for health-care-associated extensively drug-resistant Acinetobacterbaumannii infections: a case-control study [J]. PloS One,2014,9(1):85973.
  • 10Kim SH,Ha US,Yoon BI. Microbiological and clinicalcharacteristics in acute bacterial prostatitis according tolower urinary tract manipulation procedure [J]. J InfectChemother,2014,20(1): 38-42.

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