摘要
目的分析血浆铁蛋白和血清微量元素水平与儿童反复呼吸道感染(recurrent respiratory tract infection,RRTI)的相关性。方法回顾性分析2017年5月至2019年8月本院收治的80例RRTI患儿(疾病组)和健康体检的35例儿童(健康组)的临床资料,比较疾病组和健康组儿童以及疾病组不同病情严重程度患儿血浆铁蛋白和血清微量元素水平,并分析血浆铁蛋白和血清微量元素水平与RRTI患儿病情严重程度的相关性以及血浆铁蛋白与血清微量元素水平之间的关系。结果疾病组患儿血浆铁蛋白、血清Ca、Mg、Fe、Zn水平均显著低于健康组(均P<0.05)。随着病情的加重,RRTI患儿血浆铁蛋白和血清Ca、Mg、Fe、Zn水平均显著下降(均P<0.05)。血浆铁蛋白和血清Ca、Mg、Fe、Zn水平与RRTI患儿病情严重程度呈明显负相关(r=-0.521、-0.658、-0.606、-0.568,均P<0.05)。Spearman相关分析提示RRTI患儿血浆铁蛋白水平与血清Fe、Zn、Ca水平均呈明显正相关(r=0.302、0.316、0.358,均P<0.05),与血清Mg水平无显著相关性(P>0.05)。结论血浆铁蛋白和血清Mg、Fe、Zn、Ca水平与儿童RRTI病情严重程度存在明显的相关性,可为制订儿童RRTI的防治方案提供参考。
Objective Analysis of the relationship between the levels of plasma ferritin and serum trace elements and recurrent respiratory tract infection in children(RRTI).Method The clinical data of 80 children with RRTI(disease group)and 35 healthy children(health group)admitted to our hospital from May 2017 to August 2019 were analyzed retrospectively,the levels of plasma ferritin and serum trace elements were compared between disease group and healthy group and children with different severity of disease group.The correlation between the levels of plasma ferritin and serum trace elements and the severity of RRTI and the relationship between plasma ferritin and serum trace elements were analyzed.Result The levels of plasma ferritin,serum Ca,Mg,Fe and Zn in disease group were significantly lower than those in healthy group(all P<0.05).With the aggravation of disease,the levels of plasma ferritin and serum Ca,Mg,Fe and Zn decreased significantly in children with RRTI(all P<0.05).The levels of plasma ferritin and serum Ca,Mg,Fe and Zn were negatively correlated with the severity of RRTI(r=-0.521,-0.658,-0.606,-0.568,all P<0.05).Spearman correlation analysis showed that the level of plasma ferritin was positively correlated with the levels of serum Fe,Zn and Ca(r=0.302,0.316,0.358,all P<0.05),but not with the level of serum Mg(P>0.05).Conclusion The levels of plasma ferritin and serum Mg,Fe,Zn,Ca are significantly correlated with the severity of RRTI in children,which can provide reference for the prevention and treatment of RRTI in children.
作者
敬存婷
任露
JING Cun-ting;REN Lu(Department of Child Health Care,Sichuan Maternal and Child Health Hospital,Chengdu 610000,China)
出处
《中国医学前沿杂志（电子版）》
2019年第11期54-58,共5页
Chinese Journal of the Frontiers of Medical Science(Electronic Version)
关键词
反复呼吸道感染
儿童
铁蛋白
微量元素
相关性
Recurrent respiratory tract infection
Children
Ferritin
Trace elements
Correlation
