摘要
目的:分析MRI相位对比成像(PC-MRI)在中脑导水管区脑脊液检测时的流动曲线,以及流速编码(VENC)、导水管位置、ROI面积3个因素对结果的影响。方法:纳入30例志愿者,10例(第1组)定位导水管中段,VENC=5、10、20、70 cm/s扫描4次,ROI=0.03 cm^2;10例(第2组)VENC=20 cm/s、于导水管上口、中段、下口扫描3次,ROI=0.03 cm^2;10例(第3组)定位导水管中段、VENC=20 cm/s扫描,绘制ROI=0.01、0.02、0.03、0.04 cm 24次。ROI绘制后系统自动生成流动曲线和各流动参数。结果:①流动曲线呈正、余弦波和“U”型波多种形态。②第1组VENC=5 cm/s均见混淆伪影、流动曲线呈无规律波浪状,与VENC=10、20、70 cm/s时的峰值流速、绝对每博输出量(ASV)差异均有统计学意义(均P<0.05);VENC=10、20、70 cm/s时无混淆伪影,流动曲线呈规律性,各测量结果差异均无统计学意义(均P>0.05)。③第2组导水管不同部位所测流动参数,差异均无统计学意义(均P>0.05)。④第3组ASV随ROI增大而增加,差异有统计学意义(P<0.05);不同ROI时的峰值流速、平均流速及回返系数差异均无统计学意义(均P>0.05)。结论:①导水管区脑脊液流动曲线形态多样,但均反映双向往复波动式流动,延长诸波形具有一致性。②VENC=5 cm/s取值过低,70 cm/s取值略高,10~20 cm/s较合理;③扫描导水管不同部位对测量结果无影响;④ROI面积与ASV及回返系数呈正比,对峰值流速、平均流速无影响。
Objective:To analyze the flow curve of magnetic resonance phase-contrast imaging(PC-MRI)in cerebrospinal fluid detection in the middle cerebral aqueduct area,and the influence of three factors,velocity encoding(VENC),aqueduct location and ROI area,on the results.Methods:①Ten volunteers were employed to locate the middle part of the aqueduct,and VENC=5,10,20,and 70 cm/s were scanned 4 times,with ROI=0.03 cm 2.②Another 10 volunteers,VENC=20 cm/s,scanning the upper,middle and lower orifice of the aqueduct for 3 times,ROI=0.03 cm 2.③Another 10 volunteers,positioned the middle part of the aqueduct,VENC=20 cm/s scanning,and drew ROI=0.01,0.02,0.03,0.04 cm 2 for 24 times.After ROI drawing,the system automatically generates flow curves and flow parameters.Results:①The flow curve presented various forms of positive,cosine wave and“U”wave.②Confound artifacts were observed at VENC=5 cm/s,and the flow curve presented irregular wavy shape,with statistically significant differences with VENC=10,20,70 cm/s in peak velocity,absolute stroke volume(ASV),and return coefficient(P<0.05).There was no confound artifact at VENC=10~70 cm/s,the flow curve was regular,and there was no statistically significant difference among the measurement results(P>0.05).③There was no statistically significant difference in flow parameters measured at different parts of the aqueduct(P>0.05).④ASV increased with the increase of ROI area,and the difference was statistically significant(P<0.05).There was no significant difference in ROI peak velocity,average velocity and return coefficient(P>0.05).Conclusions:①The CSF flow curves in the aqueduct area are varied,but all reflect the two-way reciprocating wave flow,and the prolongation waveforms are consistent.②VENC=5 cm/s is too low,VENC=70 cm/s is slightly higher,VENC=10~20 cm/s is more reasonable.③Different parts of the aqueduct have no influence on the measurement results.④ROI area is positively proportional to ASV and return coefficient,but has no influence on peak velocity and average velocity.
作者
盛范龙
王长军
董辉
修建军
Sheng Fanlong;Wang Changjun;Dong Hui;Xiu Jianjun(Department of Medical Imaging,Shandong Provincial Hospital,Jinan,250021,China)
出处
《中国中西医结合影像学杂志》
2019年第6期562-565,共4页
Chinese Imaging Journal of Integrated Traditional and Western Medicine
基金
山东省自然科学基金(ZR2017MH018)
关键词
脑脊液
流动曲线
回返系数
磁共振成像
Cerebrospinal fluid
Flow curve
Return coefficient
Magnetic resonance imaging
