摘要
目的比较腹腔镜术后辅助应用孕三烯酮与米非司酮治疗子宫内膜异位症(EMT)的临床效果及安全性。方法将我院收治的62例EMT患者随机分为对照组和观察组,各31例。两组均采用腹腔镜手术治疗。在此基础上,对照组给予孕三烯酮,观察组给予米非司酮。对比两组治疗效果。结果治疗后,两组的LH、FSH、P、CA125、MMP-9、Ang-2、Tie-2水平均降低,且观察组低于对照组(P<0.05)。两组不良反应总发生率比较,差异不显著(P>0.05)。结论腹腔镜术后辅助应用米非司酮治疗EMT的效果更好,更有利于改善激素、血生化指标及血管生长相关调节因子水平,安全可靠。
Objective To compare the clinical efficacy and safety of gestrinone and mifepristone on endometriosis(EMT)after laparoscopic surgery. Methods Sixty-two EMT patients were randomly divided into control group and observation group, with 31 cases in each group. Laparoscopic surgery was given in both groups. On this basis, the control group was given gestrinone, the observation group was given mifepristone. The therapeutic effects of the two groups were compared.Results After treatment, the levels of LH, FSH, P, CA125, MMP-9, Ang-2 and Tie-2 in the two groups decreased, and those of the observation group were lower than the control group(P<0.05). There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05). Conclusion Mifepristone is more effective in the treatment of EMT after laparoscopic surgery, which is more conducive to the improvement of the levels of hormone, blood biochemical indicators and vascular growth related regulatory factors, with safety and reliability.
作者
范晓玲
陈芳红
FAN Xiao-ling;CHEN Fang-hong(the First People's Hospital of Xianyang,Xianyang 712000;Xianyang Rainbow Hospital,Xianyang 712000,China)
出处
《临床医学研究与实践》
2019年第34期111-112,共2页
Clinical Research and Practice
