摘要
Objective:To systematically evaluate the therapeutic effects of inspiratory muscle training(IMT)on cardiopulmonary functions in patients with heart failure.Methods:PubMed,EMbase,the Cochrane Library,Web of Science,CBM,WanFang Data,VIP,and CNKI databases were searched to collect randomized controlled trials about the effects of IMT on cardiopulmonary function in patients with heart failure.Meta-analysis was performed using RevMan 5.3 software after two researchers independently screened the literatures,extracted the data,and evaluated the risk of bias.Results:A total of 20 articles with 1,415 patients were included.Meta-analysis showed that IMT was able to increase the 6-minute walking distance(mean difference(MD)=59.41,95%confidence interval(CI)(51.02–67.80),P<0.001)and maximum inspiratory pressure(MD=15.59,95%CI(12.96–18.21),P<0.001)in patients with heart failure compared with the control group.But there was no statistical difference in peak oxygen uptake(MD=1.37,95%CI(?0.57–3.30),P=0.17),first second forced expiratory volume(MD=?5.79,95%CI(?12.23–0.65),P=0.08)and forced vital capacity(MD=?0.45,95%CI(?6.39–5.49),P=0.88)between the control and the experimental group.Conclusion:Available evidence suggested that IMT seemed to be a useful strategy for improving exercise capacity and inspiratory muscle strength in heart failure patients.Limited by the quantity and quality of the included studies,the above conclusions need to be verified by more high-quality studies.