摘要
目的探究对重症肺炎患者实施头孢哌酮/舒巴坦与盐酸莫西沙星联合治疗的效果。方法 106例重症肺炎患者,随机分为观察组和对照组,每组53例。观察组患者应用头孢哌酮/舒巴坦联合盐酸莫西沙星治疗,对照组患者应用头孢哌酮/舒巴坦治疗。对比两组患者的治疗效果、症状消失时间及不良反应发生情况。结果观察组患者总有效率高于对照组,差异具有统计学意义(P<0.05)。观察组患者发热、咳痰、肺部啰音消失时间分别为(2.25±0.34)、(7.10±1.25)、(5.45±1.56)d,均短于对照组的(3.68±0.98)、(9.73±2.62)、(8.36±2.78)d,差异具有统计学意义(P<0.05);两组患者不良反应发生率对比差异无统计学意义(P>0.05)。结论对重症肺炎患者实施头孢哌酮/舒巴坦与盐酸莫西沙星联合治疗的效果较单一用药更佳,更有助于缓解患者病情。
Objective To investigate the effect of cefoperazone/sulbactam combined with moxifloxacin hydrochloride in the treatment of severe pneumonia, so as to provide guidance for clinical practice. Methods A total of 106 severe pneumonia patients were randomly divided into observation group and control group, with 53 cases in each group. The observation group was treated by cefoperazone/sulbactam combined with moxifloxacin hydrochloride, and the control group was treated by cefoperazone/sulbactam. The therapeutic effect, disappearance time of symptoms and occurrence of adverse reactions between the two groups. Results The total effective rate in the observation group was higher than that in the control group, and the difference was statistically significant(P<0.05). The disappearance time of fever, expectoration and lung rales were(2.25±0.34),(7.10±1.25) and(5.45±1.56) d in the observation group, which were shorter than(3.68±0.98),(9.73±2.62) and(8.36±2.78) d in the control group, and their difference was statistically significant(P<0.05). There was no statistically significant difference in incidence of adverse reactions between the two groups(P>0.05). Conclusion Cefoperazone/sulbactam combined with moxifloxacin hydrochloride shows better effect on severe pneumonia patients than that of single medication, which is more helpful to alleviate the patients’ condition.
作者
容建创
陈海燕
RONG Jian-chuang;CHEN Hai-yan(Department of Pharmacy,Foshan First People’s Hospital(Foshan Hospital Affiliated to Sun Yat-sen University),Foshan 528000,China)
出处
《中国现代药物应用》
2019年第23期102-103,共2页
Chinese Journal of Modern Drug Application
关键词
重症肺炎
头孢哌酮/舒巴坦
盐酸莫西沙星
Severe pneumonia
Cefoperazone/sulbactam
Moxifloxacin hydrochloride
