摘要
目的分析杭州市拱墅区女性人乳头瘤病毒(HPV)感染和HPV基因型分布。方法选择2015-2018年杭州师范大学附属医院就诊的16-82岁女性,进行HPV基因型检测和回顾性分析。结果调查对象HPV检测总阳性率为29.27%(11560/39488);阳性率最高的5种HPV基因型为HPV52(6.71%)、HPV16(4.01%)、HPV58(3.21%)、HPV81(3.03%)、HPV53(2.95%);≤20岁、21-30岁、31-40岁、41-50岁、51-60岁、61-70岁、≥71岁调查对象的HPV阳性率分别为48.8%、29.7%、27.4%、28.2%、33.3%、31.3%、23.3%。结论杭州市拱墅区女性HPV感染以≤20岁和51-60岁为主,优势基因型为HPV52、HPV16、HPV58。
Objective To determine presence of human papillomavirus(HPV)infection and determine HPV genotypes among females in Gongshu district of Hangzhou city.Methods We selected 16-82-year-old females who visited the Affiliated Hospital of Hangzhou Normal University during 2015-2018 and detected HPV genotypes for a retrospective analysis.Results The overall HPV positivity rate was 29.27%(11560/39488),with the five most common genotypes being HPV52(6.71%),HPV16(4.01%),HPV58(3.21%),HPV81(3.03%),and HPV53(2.95%).The HPV positivity rates for≤20,21-30,31-40,41-50,51-60,61-70,and≥71 year olds were 48.8%,29.7%,27.4%,28.2%,33.3%,31.3%,and 23.3%,respectively.Conclusion HPV infection was common among≤20 and 51-60 year olds in Gongshu district of Hangzhou city.The predominant genotypes were HPV52,HPV16,and HPV58.
作者
杨晓
张敏
Yang Xiao;Zhang Min(Affiliated Hospital of Hangzhou Normal University,Hangzhou 310015,Zhejiang,China;Institute of Cancer Research and Basic Medical Sciences of Chinese Academy of Sciences,Cancer Hospital of University of Chinese Academy of Sciences,Zhejiang Cancer Hospital,Hangzhou 310022,Zhejiang,China)
出处
《中国疫苗和免疫》
北大核心
2019年第5期540-544,共5页
Chinese Journal of Vaccines and Immunization
基金
浙江省医药卫生科技计划项目(2020RC045)
关键词
人乳头瘤病毒
感染
基因型
Human papillomavirus
Infection
Genotype
