期刊文献+

新一代左心室磁悬浮辅助泵血流动力学分析 被引量:3

Hemodynamic Analysis on Meglev Left Ventricular Assist Device of a New Generation
原文传递
导出
摘要 目的 降低左心室磁悬浮辅助泵的血栓形成概率和溶血风险,提升辅助泵供血效率。方法 利用计算流体动力学方法,研究泵体出口直径、出口角度、出口与泵内壁面连接处圆角尺寸和转子与壳体间间隙对流场的影响,优化泵体内部结构,改善流体动力学性能。结果 新一代左心室磁悬浮辅助泵与上一代辅助泵相比,泵内壁面最大壁面剪切应力(wall shear stress,WSS)降低约23. 6%,辅助泵内转子壁面最大WSS降低约47. 4%,WSS>200 Pa区域面积降低约76. 2%,出口流量提升约14. 4%。结论 新一代左心室磁悬浮辅助泵内部血流流迹趋于平缓,血流流体动力学性能有综合提升。研究结果为今后左心室磁悬浮辅助泵的优化设计及相关实验研究提供参考依据。 Objective To reduce the thrombosis probability and hemolysis risk of the meglev left ventricular assist device(LVAD),so as to increase the efficiency of blood supply.Methods The influences of the pump outlet diameter,exit angle,fillet size between the outlet and the inner wall of the pump,as well as gap between the rotor and the shell on internal flow field of the pump were studied by using the computational fluid dynamics(CFD)method,so as to optimize the internal structure and improve the hydrodynamic performance of the pump.Results Compared with pump of the previous generation,the maximum wall shear stress(WSS)of the pump inner wall,the maximum WSS of the pump rotor,the area with WSS>200 Pa were reduced by 23.6%,47.4%,76.2%,respectively,while the outlet flow was increased by 14.4%.Conclusions For the meglev LVAD of the new generation,its internal blood flow tended to be smooth,and the hemodynamic performance of blood flow was improved comprehensively.The research findings provide references for optimization design of the meglev LVAD and related experimental researches in the future.
作者 牛迪 朱明新 冯海全 王坤 NIU Di;ZHU Mingxin;FENG Haiquan;WANG Kun(College of Mechanical Engineering,Inner Mongolia University of Technology,Hohhot 010000,China)
出处 《医用生物力学》 EI CAS CSCD 北大核心 2019年第5期468-472,共5页 Journal of Medical Biomechanics
基金 国家自然科学基金项目(51565045)
关键词 左心室辅助泵 磁悬浮 计算流体动力学 壁面剪切应力 left ventricular assist device(LVAD) meglev computational fluid dynamics(CFD) wall shear stress(WSS)
  • 相关文献

参考文献8

二级参考文献75

  • 1姜红,葛均波.心力衰竭流行病学特点[J].中国医学前沿杂志(电子版),2010,2(1):1-5. 被引量:90
  • 2王芳群,封志刚,曾培,茹伟民,袁海宇,钱坤喜.基于CFD的离心式人工心脏泵的溶血预测方法[J].中国生物医学工程学报,2006,25(3):338-341. 被引量:8
  • 3姜华,席光.心脏泵的研究进展[J].医疗卫生装备,2006,27(8):33-35. 被引量:11
  • 4Maciver J,Rao V,Ross H J.Quality of life for patients supported on a left ventricular assist device[J].Expert Rev Med Devices,2011,8 (3):325-337.
  • 5Tuzun E,Roberts K,Cohn W E,et al.In vivo evaluation of the heartware centrifugal ventricular assist device[J].Tex Heart Inst J,2007,34(4):406-411.
  • 6Farrar D J,Bourque K,Dague C P,et al.Design features,developmental status,and experimental results with the heartmate Ⅲ centrifugal left ventricular assist system with a magnetically levitated rotor[J].ASAIO J,2007,53(3):310-315.
  • 7Morshuis M,Schoenbrodt M,Nojiri C,et al.DuraHeart magnetically levitated centrifugal left ventricular assist system for advanced heart failure patients[J].Expert Rev Med Devices,2010,7(2):173-183.
  • 8ASTM F1841-97(2005) Standard Practice for Assessment of Hemolysis in Continuous Flow Blood Pumps[EB/OL].(2005-01-01)[2011-09-02].http://www.astm.org/Standards/F1841.htm.
  • 9Recently-Approved Devices[EB/OL].(2010-04-06)[2011-09-02].http://www.fda.gov/MedicalDevices/ProductsandMedicalProcedures/DeviceApprovalsandClearances/Recently-ApprovedDevices/default.htm.
  • 10American Heart Association. International Cardiovascular Diseases Statistics. Statistical Fact Sheet-Populations. Dallas,TX: American Heart Associations, 1-10, 2003

共引文献37

同被引文献21

引证文献3

二级引证文献4

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部