摘要
目的研究氨溴索联合阿洛西林钠治疗小儿支气管肺炎的临床效果。方法选取该院2017年1月—2018年10月收治的小儿支气管肺炎患儿60例,将其随机分为两组,各30例。采用阿洛西林钠治疗对照组,基于此联合氨溴索治疗观察组。比较两组患儿炎症因子水平变化、各症状改善时间、疗效以及不良反应。结果在炎症因子上,两组IL-6、CRP等水平对比,差异有统计学意义(t=5.234、6.274,P<0.05)。在各症状改善时间上,两组肺啰音及咳嗽消失、退热、住院等时间对比,差异有统计学意义(t=2.035、2.174、2.039、2.741,P<0.05)。在治疗有效率上,对照组为83.33%,观察组为96.67%,差异有统计学意义(χ^2=6.357,P=0.000)。在不良反应上,对照组发生率16.67%,观察组发生率为3.33%,差异有统计学意义(χ^2=4.152,P=0.000)。结论氨溴索联合阿洛西林钠治疗小儿支气管肺炎的效果显著,即可显著改善患儿炎症,快速缓解其各种症状,且不良反应少,安全性较高,值得临床应用推广。
Objective To study the clinical effect of ambroxol combined with azlocillin sodium in the treatment of children with bronchopneumonia.Methods Sixty children with bronchopneumonia in the hospital from January 2017 to October 2018 were randomly divided into two groups,30 cases each.The control group was treated with azlocillin sodium,based on this combined ambroxol treatment group.The changes of inflammatory factor levels,time to symptom improvement,efficacy and adverse reactions were compared between the two groups.Results On the inflammatory factors,there was a statistically significant difference in the levels of IL-6 and CRP between the two groups(t=5.234,6.274,P<0.05).There was a statistically significant difference in the time of pulmonary vocal and cough disappearance,fever,hospitalization,etc.between the two groups(t=2.035,2.174,2.039,2.741,P<0.05).In the treatment efficiency,the control group was 83.33%,and the observation group was 96.67%.There was a statistical difference between the two(χ^2=6.357,P=0.000).In the adverse reactions,the incidence of the control group was 16.67%,and the incidence of the observation group was 3.33%.There was a statistical difference between the two(χ^2=4.152,P=0.000).Conclusion Ambroxol combined with azlocillin sodium is effective in the treatment of children with bronchial pneumonia,which can significantly improve the inflammation of children,quickly relieve various symptoms,and has fewer adverse reactions and higher safety.It is worthy of clinical application.
作者
丁俭
DING Jian(Department of Pediatrics,Liangshan County People's Hospital,Jining,Shandong Province,272600 China)
出处
《系统医学》
2019年第21期7-9,共3页
Systems Medicine
关键词
小儿支气管肺炎
氨溴索
阿洛西林钠
临床效果
Pediatric bronchial pneumonia
Ambroxol
Azlocillin sodium
Clinical effect
