摘要
目的:观察苍附导痰汤联合来曲唑对肥胖型多囊卵巢综合征(polycystic ovary syndrome,PCOS)不孕症患者的临床疗效。方法:选取2017年1-7月笔者所在医院诊治的76例PCOS不孕症患者,将其随机分为观察组和对照组,每组38例。对照组采用来曲唑口服治疗,观察组应用苍附导痰汤联合来曲唑口服治疗,治疗6个月经周期,观察比较两组临床疗效。结果:观察组治疗总有效率显著高于对照组,差异有统计学意义(P<0.05)。观察组治疗后LH、FSH、T、BMI水平均低于对照组,差异有统计学意义(P<0.05)。观察组治疗后不良反应发生率均显著低于对照组,差异有统计学意义(P<0.05)。观察组患者治疗后1年内成功妊娠率、排卵率高于对照组,差异有统计学意义(P<0.05)。结论:苍附导痰汤联合来曲唑治疗多囊卵巢综合征不孕效果较好,能提高PCOS患者排卵率、妊娠率,不良反应少,值得推广使用。
Objective: To observe the clinical effects of Cangfu Daotan Decoction combined with Letrozole in the treatment of obesity infertility with polycystic ovary syndrome(PCOS). Method: A total of 76 patients with infertility PCOS admitted in our hospital from January to July 2017 were selected. They were randomly divided into the observation group and the control group, with 38 patients in each group. The control group was treated with Letrozole orally, andthe observation group was treated with Cangfu Daotan Decoction combined with Letrozoleorally for 6 menstrual cycles. The clinical efficacy of the two groups was observed and compared. Result: The total effective rate in the observation group was significantly higher than that in the control group, and the difference was statistically significant(P<0.05). After treatment, the LH, FSH, T and BMI in the observation group were all lower than those in the control group, and the differences were statistically significant(P<0.05). The incidence of adverse reactions in the observation group was significantly lower than that in the control group, the difference was statistically significant(P<0.05). The successful pregnancy rate and ovulation rate in the observation group were higher than those in the control group with in 1 year after treatment, the difference was statistically significant(P<0.05). Conclusion: Cangfu Daotan Decoction combined with Letrozole has a better effect in the treatment of polycystic ovary syndromeare with infertility, which can improve ovulation rate and pregnancy rate of PCOS patients, and less adverse reactions, it is worth promoting.
作者
张秋仔
李宇青
倪凯宾
郭进
ZHANG Qiuzi;LI Yuqing;NI Kaibin;GUO Jin(Mindong Hospital Affiliated to Fujian Medical University,Fu’an 355000,China)
出处
《中外医学研究》
2019年第33期18-20,共3页
CHINESE AND FOREIGN MEDICAL RESEARCH
基金
2018年福建中医药大学校管科研课题项目(项目编号：XB2018120)
关键词
苍附导痰汤
来曲唑
肥胖型多囊卵巢综合征
不孕症
Cangfu Daotan Decoction
Letrozole
Obesity polycystic ovary syndrome
Infertility
