摘要
目的探讨体素内不相干运动(IVIM)多模型参数对I期子宫内膜癌(EC)与子宫内膜息肉(EP)的鉴别价值。方法回顾性分析经病理证实的31例I期EC患者(EC组)及14例EP患者(EP组)的临床及影像资料,患者术前均行1.5T MR检查,含IVIM序列(b=0、20、50、100、150、200、400、800、1200、2000、3000 s/mm^2)。测量并比较2组间病灶的IVIM多模型参数值,包括标准表观扩散系数(ADC-stand)、慢速表观扩散系数(ADC-slow)、快速表观扩散系数(ADC-fast)、灌注分数(f)、扩散分布指数(DDC)及拉伸指数(α)。采用ROC曲线评估IVIM参数对I期EC与EP的鉴别诊断效能。结果EC组ADC-stand值、ADC-slow值、f值、DDC值及α值均小于EP组,ADC-fast值大于EP组,差异均有统计学意义(P均=0.001)。ROC曲线结果显示,ADC-stand值、ADC-slow值、ADC-fast值、f值、DDC值及α值对I期EC与EP均有鉴别诊断价值,AUC分别为0.885、0.877、0.919、0.926、0.906、0.902(P均<0.05)。结论IVIM序列多模型参数能够有效鉴别I期EC与EP。
Objective To investigate the value of the multiple model parameters of intravoxel incoherent motion(IVIM)in identification of stageⅠendometrial carcinoma(EC)and endometrial polyp(EP).Methods The clinical and imaging data of 31 patients with stageⅠEC(group EC)and 14 patients with EP(group EP),confirmed by postoperative pathological examination,were retrospectively analyzed,all patients were performed on 1.5T MR(including IVIM sequence,b=0,20,50,100,150,200,400,800,1200,2000,3000 s/mm^2)before operation.The IVIM multi-model parameter values of the lesions were measured and compared between the two groups,including the standard apparent diffusion coefficient(ADC-stand),slow-apparent diffusion coefficient(ADC-slow),fast-apparent diffusion coefficient(ADC-fast),perfusion fraction(f),distributed diffusion coefficient(DDC)and water molecular diffusion heterogeneity index(α).The ROC curve was used to evaluate the differential diagnostic efficacy of IVIM parameters for stageⅠEC and EP.Results The ADC-stand value,ADC-slow value,f-value,DDC value andαvalue of the EC group were all less than the EP group,and the ADC-fast value was greater than the EP group(all P=0.001).ROC curve results showed the standard ADC value,ADC-slow value,ADC-fast value,f value,DDC value andαvalue had differential diagnostic value for stageⅠEC and EP,the AUC was 0.885,0.877,0.919,0.926,0.906 and 0.902,respectively(all P<0.05).Conclusion The multi-model parameters of IVIM sequence can effectively identify stageⅠEC and EP.
作者
田士峰
刘爱连
陈安良
杨伟萍
鞠烨
宋清伟
姜艳
TIAN Shifeng;LIU Ailian;CHEN Anliang;YANG Weiping;JU Ye;SONG Qingwei;JIANG Yan(Department of Radiology,the First Affiliated Hospital of Dalian Medical University,Dalian 116011,China)
出处
《中国医学影像技术》
CSCD
北大核心
2019年第12期1856-1860,共5页
Chinese Journal of Medical Imaging Technology
基金
首都科技领军人才培养工程(Z181100006318003)
关键词
癌
子宫内膜样
息肉
磁共振成像
体素内不相干运动
carcinoma
endometrioid
polyps
magnetic resonance imaging
intravoxel incoherent motion
