摘要
前列腺癌作为中国男性常见的恶性肿瘤之一.大多数患者被诊断为前列腺癌时已处于中晚期,许多患者错过最佳治疗时机.大多数前列腺癌患者经去势治疗后会进展成为去势抵抗性前列腺癌,其可供选择的治疗方案局限.免疫治疗在肿瘤研究中已获得许多突破性进展,并且免疫疗法已被证实能为肿瘤患者带来生存获益,但不同的肿瘤免疫治疗方案对前列腺癌患者获益不一.本文将阐述免疫治疗在前列腺癌的治疗作用及其分子基础研究.
Prostate cancer is one of the common malignant tumors in Chinese men.Most patients are diagnosed with prostate cancer at an advanced stage,and many patients fail to take the best treatment opportunity.The majority of prostate cancer patients progress to castration-resistant prostate cancer after castration,and their alternative treatment options are limited.Immunotherapy has made many breakthroughs in cancer research,and immunotherapy has been proven to bring survival benefits to patients with cancer.However,difTerent types of immunotherapy regimens benefit differently for prostate cancer patients.This article will describe the therapeutic effects of immunotherapy in prostate cancer and its basis research.
作者
朱学进
钟惟德
Zhu Xuejin;Zhong Weide(Department of Urology,Guangdong Key Laboratory of Clinical Molecular Medicine and Diagnostics,Guangzhou First People,s Hospital,the Second Affiliated Hospital of South China University of Technology,Guangzhou 510180,China)
出处
《中华实验外科杂志》
CAS
CSCD
北大核心
2019年第12期2130-2136,共7页
Chinese Journal of Experimental Surgery
关键词
前列腺癌
免疫治疗
Prostate cancer
Immunotherapy
