摘要
目的探究3D腹腔镜前列腺癌根治术治疗局限性前列腺癌的临床疗效。方法选取2017年10月至2018年10月我院泌尿外科收治的108例局限性前列腺癌患者,按不同的手术方案分为对照组(行开腹手术)和观察组(行3D腹腔镜前列腺癌根治术),每组54例。比较2组手术情况、尿流动力学、并发症及预后情况。结果2组患者手术时间比较差异无统计意义(P>0.05);观察组术中出血量少于对照组,留置尿管时间、首次排气时间、住院时间短于对照组,术后疼痛评分低于对照组,差异均有统计学意义(P<0.01);观察组术后残余尿量(PVR)、充盈期膀胱顺应性值(BC)、逼尿肌不稳定率(DI)低于对照组,最大尿流率(Qmax)、最大尿流率时逼尿肌压力(Pdet at Qmax)高于对照组,差异有统计学意义(P<0.01);观察组术后并发症发生率低于对照组,差异有统计学意义(P<0.05);术后随访1年,2组患者完全尿控率、生化复发率比较差异无统计意义(P>0.05)。结论局限性前列腺癌应用3D腹腔镜前列腺根治术治疗效果显著,术中出血量少,术后疼痛轻,并发症少,且能有效改善尿流动力学指标,降低病灶复发率,改善预后。
Objective To observe the clinical effect of 3D laparoscopic radical prostatectomy for localized prostate cancer.Methods The clinical data of 108 patients with localized prostate cancer were collected from those who had received treatment in our hospital from October 2017 to October 2018.According to the different surgical procedures,they were divided into two groups with 54 cases in each group.The control group underwent open surgery,whereas the observation group received 3D laparoscopic radical prostatectomy.The surgical indexes,urodynamics,complications and prognosis of the two groups were compared.Results There was no statistical difference in operation time between patients of the two groups(P>0.05).The intraoperative blood loss in the observation group was less than that in the control group,the duration of indwelling catheter,the duration of first exhaust,and the length of hospitalization in the observation group were shorter than those in the control group,and the postoperative pain score in the observation group was lower than that in the control group,with statistically significant differences(P<0.01).The postoperative PVR,BC and DI in the observation group were lower than those in the control group,and the Qmax and Pdet at Qmax in the observation group were higher than those in the control group,with statistically significant differences(P<0.01).The incidence of complications in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).There was no statistically significant difference in the complete urinary control rate and the biochemical recurrence rate between the two groups during the follow-up of one year(P>0.05).Conclusion The application of 3D laparoscopic radical prostatectomy for localized prostate cancer has a significant effect,with less intraoperative blood loss,less postoperative pain and fewer complications.In addition,it can effectively improve the indicators of urinary flow dynamics,reduce the recurrence rate of lesions and improve the prognosis.
作者
斯钦布和
易发现
王国强
朱小军
SI Qinbuhe;YI Fa-xian;WANG Guo-qiang;ZHU Xiao-jun(Department of Urology Surgery,Affiliated Hospital of Inner Mongolia Medical University,Hohhot Inner Mongolia 010058,China)
出处
《局解手术学杂志》
2019年第12期978-982,共5页
Journal of Regional Anatomy and Operative Surgery
基金
内蒙古自治区科技计划项目(1505015)
