摘要
目的比较经尿道2μm激光前列腺剜除术和前列腺电切术(TURP)对大体积良性前列腺增生(BPH)患者的治疗效果及安全性。方法回顾性分析于我院进行治疗的82例大体积BPH(前列腺体积>80mL)患者临床资料,根据其术式分为经尿道2μm激光前列腺剜除术组(2μm激光组)和TURP组,比较两组围术期指标,手术前后血清前列腺特异性抗原(PSA)和尿白细胞水平,最大尿流率(Qmax)和残余尿量(PVRU),国际前列腺症状评分(IPSS),术后并发症。结果2μm激光组术中出血量、术后膀胱持续冲洗时间、术后留置导尿管时间及术后住院时间均少于TURP组(P<0.05),手术时间、切除腺体质量与TURP组比较差异均无统计学意义(P>0.05),术后1个月血清PSA、Qmax、PVRU水平及IPSS评分与TURP组均无显著差异(P>0.05),术后1个月尿白细胞少于TURP组(P<0.05),术后并发症总发生率低于TURP组(P<0.05)。结论经尿道2μm激光前列腺剜除术和TURP术治疗大体积BPH均有较好效果,且经尿道2μm激光前列腺剜除术更能够减少术中出血量和术后并发症发生,安全性相对更高。
Objective To compare the curative effect and safety of transurethral 2μm laser prostatectomy and transurethral resection of prostate(TURP)for patients with large volume benign prostatic hyperplasia(BPH).Methods The clinical data of 82 patients with large volume BPH(prostate volume greater than 80 mL)who were treated in the hospital were retrospectively analyzed.According to the surgical procedures,they were divided into transurethral 2μm laser prostatectomy group(2μm laser group)and TURP group.The perioperative indicators,levels of serum prostate specific antigen(PSA)and urine leukocyte before and after surgery,maximum urinary flow rate(Qmax)and postvoid residual urine(PVRU),international prostate symptom score(IPSS)and postoperative complications were compared between the two groups.Results The intraoperatve blood loss,the duration time of postoperative bladder irrigation,the postoperative indwelling catheter time and postoperative hospital stay in 2 pim laser group were all shorter than those in the TURP group(P<0.05).There was no significant difference in the operation time and the weight of the resected gland between the two groups(P>0.05).There was no significant difference in levels of serum PSA,Qmax,PVRU and IPSS scores between the two groups at 1 month after surgery(P>0.05).The urinary leukocytes were less than those in the TURP group at 1 month after surgery(P<0.05),while the total incidence of postoperative complications was lower than that in TURP group(P<0.05).Conclusion The curative effects are all good with transurethral 2μm laser prostatectomy and transurethral resection of prostate in treating large volume BPH,and the former can more reduce intraoperative blood loss and postoperative complications.And the safety is relatively higher.
作者
屈昭义
毛敏
Qu Zhaoyi;Mao Min(Department of Urology,Tongjiang County People's Hospital,Tongjiang 636700,Sichuan,China;Department of Urology,West China Hospital of Sichuan University,Chengdu 610044,Sichuang,China)
出处
《中国男科学杂志》
CAS
CSCD
2019年第5期32-35,共4页
Chinese Journal of Andrology
关键词
激光疗法
经尿道前列腺切除术
前列腺增生
疗效比较研究
laser therapy
transurethral resection of prostate
benign prostatic hyperplasia
coparative affectiveness
