期刊文献+

幽门螺杆菌感染胃溃疡患者应用抗菌药物治疗的效果分析 被引量:2

下载PDF
导出
摘要 目的分析幽门螺杆菌感染胃溃疡患者应用抗菌药物治疗的临床疗效。方法 68例幽门螺杆菌感染胃溃疡患者,随机分为参照组和研究组,各34例。参照组给予奥美拉唑治疗,研究组在参照组基础上给予阿莫西林和甲硝唑治疗。比较两组治疗前后的血清炎性因子水平及临床疗效。结果治疗前两组胃蛋白酶原(PG)Ⅰ、PGⅡ、C反应蛋白(CRP)比较差异无统计学意义(P>0.05);治疗后两组PGⅠ、PGⅡ、CRP均较治疗前显著下降,差异均有统计学意义(P<0.05)。治疗后,研究组PGⅠ、PGII、CRP分别为(210.09±15.10)ng/L、(8.85±3.45)ng/L、(2.12±1.26)mg/dl,显著低于参照组的(229.66±15.09)ng/L、(13.35±3.38)ng/L、(5.85±1.02)mg/dl,差异均有统计学意义(P<0.05)。研究组总有效率为91.18%,明显高于参照组的70.59%,差异具有统计学意义(P<0.05)。结论幽门螺杆菌感染胃溃疡患者应用奥美拉唑、阿莫西林和甲硝唑联合治疗疗效确切,可有效改善患者的临床症状。
作者 崔忠玉
出处 《中国实用医药》 2019年第35期129-130,共2页 China Practical Medicine
  • 相关文献

二级参考文献60

  • 1Chiu PW,Chan FK,Lau JY.Endoscopic suturing for ulcer exclusion in patients with massively bleeding large gastric ulcer[J].Gastroenterology,2015,149(1):29-30.
  • 2Judd S,Vanama R,Levi E,et al.Splenic abscess:a rare adverse event of a benign penetrating gastric ulcer[J].Gastrointest Endosc,2015,82(1):174-175.
  • 3Chau E,Youn H,Ren-Fielding CJ,et al.Surgical management and outcomes of patients with marginal ulcer after Roux-en-Y gastric bypass[J].Surg Obes Relat Dis,2015,11(5):1071-1075.
  • 4Huang HH,Chen HS,Chen CY.Association of short-term proton pump inhibitor therapy with weight gain in patients older than 40years with gastric ulcer[J].Surg Obes Relat Dis,2015,11(5):1187-1189.
  • 5Trejo-de lOA,Torres J,Sanchez-Zauco N,et al.Polymorphisms in TLR9but not in TLR5increase the risk for duodenal ulcer and alter cytokine expression in the gastric mucosa[J].Innate Immun,2015,21(7):706-713.
  • 6Wang XD,Wei W,Wang PF,et al.Synthesis,molecular docking and biological evaluation of 3-arylfuran-2(5H)-ones as anti-gastric ulcer agent[J].Bioorg Med Chem,2015,23(15):4860-4865.
  • 7Chang X,Luo F,Jiang W,et al.Protective activity of salidroside against ethanol-induced gastric ulcer via the MAPK/NF-κB pathway in vivo and in vitro[J].Int Immunopharmacol,2015,28(1):604-615.
  • 8Zhao Z,Gong S,Wang S,et al.Effect and mechanism of evodiamine against ethanol-induced gastric ulcer in mice by suppressing Rho/NF-kB,pathway[J].Int Immunopharmacol,2015,28(1):588-595.
  • 9林土坤,龙伟东,陈朝阳.埃索美拉唑及奥美拉唑治疗Hp阳性慢性胃炎的疗效比较[J].临床合理用药杂志,2010,3(16):17-18. 被引量:29
  • 10朱虹,廖江涛,李亲亲,陈刚,肖梅玉.四联疗法治疗幽门螺杆菌阳性胃溃疡的疗效观察[J].现代生物医学进展,2011,11(7):1330-1332. 被引量:44

共引文献154

同被引文献9

引证文献2

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部