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罗哌卡因复合吗啡鞘内注射治疗顽固性癌痛的疗效 被引量:2

Curative effects of ropivacaine combined with intrathecal injection of morphine in treatment of intractable cancer pain
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摘要 目的对罗哌卡因复合吗啡鞘内注射治疗顽固性癌痛的临床疗效进行分析。方法将2018年1~12月我院收治30例顽固性癌痛患者作为此次研究对象,均予以罗哌卡因复合吗啡鞘内注射治疗的方式,对比治疗前后的效果。结果 (1)治疗后患者NRS评分与吗啡日用剂量均低于治疗前,差异有统计学意义(P<0.05)。(2)治疗后患者生活质量评分(食欲、睡眠、精神状况、社会交流、情绪、工作)高于治疗前,差异有统计学意义(P<0.05)。(3)治疗后患者呕吐恶心、嗜睡发生率低于治疗前,差异有统计学意义(P<0.05)。结论罗哌卡因复合吗啡鞘内注射治疗顽固性癌痛的效果较为理想,不仅缓解了疼痛,更提高了患者的生活质量,是治疗顽固性癌痛的首选药物。 Objective To analyze clinical curative effects of ropivacaine combined with intrathecal injection of morphine in treatment of intractable cancer pain. Methods 30 patients with intractable cancer pain who were admitted and treated in our hospital from January to December 2018 were selected as research objects in the study.All patients were given ropivacaine combined with intrathecal injection of morphine.The curative effects before and after treatment were compared. Results(1)The NRS score and the daily dose of morphine after treatment were lower than those before the treatment.The difference was statistically significant(P<0.05).(2)The quality of life score(appetite,sleep,mental condition,social communication,mood,work)of patients after treatment was higher than that of the control group,and the difference in data was statistically significant(P<0.05).(3)The incidence of vomiting and nausea and sleepiness in patients after treatment was lower than that before treatment,and the difference in data was statistically significant(P<0.05). Conclusion The curative effect of ropivacaine combined with intrathecal injection of morphine in treatment of intractable cancer pain is ideal.It not only relieves the pain,but also improves the quality of life of the patient.It is the preferred drug for the treatment of intractable cancer pain.
作者 黄海娜 方伟杰 HUANG Haina;FANG Weijie(Puning People’s Hospital,Guangdong,Puning 515300,China)
出处 《中国医药科学》 2019年第21期168-170,共3页 China Medicine And Pharmacy
关键词 罗哌卡因 吗啡 鞘内注射 顽固性癌痛 Ropivacaine Morphine Intrathecal injection Intractable cancer pain
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