摘要
肝衰竭是多种因素引起的严重肝脏损害,导致其合成、解毒、排泄和生物转化等功能发生严重障碍或失代偿,出现以凝血机制障碍和黄疸、肝性脑病、腹水等为主要表现的一组临床症候群。肝衰竭病情进展迅速,病死率高,预后差。病因多为疫毒或湿毒痰邪,病机多为疫毒炽盛,直中肝脏,化火生风;或热邪入里,伤及营血阴液,虚风内动;或痰湿毒邪伤脾,脾虚湿盛,浊毒不化,痰蒙清窍,脉络瘀阻。病理因素多为毒、热、虚、风、痰、湿、瘀,病机特点是疫毒炽盛,湿热瘀阻或脾肾阳虚,痰毒阻络。疫毒炽盛,热入营血,耗血动血,则给予“凉血散血”,予清热解毒,凉血活血治疗;脾肾阳虚、痰毒阻络则给予健脾温肾,化痰泻浊,活血通络,宣畅气机治疗。而对于毒邪耗伤气阴,脉络瘀阻者,则应予益气养阴,活血通脉治疗。
Liver failure is a serious liver damage caused by many factors,which leads to serious disorders or decompensation of its functions such as synthesis,detoxification,excretion and biotransformation,and a group of clinical symptoms characterized by coagulation disorders and jaundice,hepatic encephalopathy,ascites,etc.Liver failure progresses rapidly with high mortality and poor prognosis.The etiology is mostly epidemic toxin,or dampness and phlegm.And the pathogenesis is mostly as follows:epidemic toxin is high enough to straightly damage liver and then cause fire and wind;or heat pathogen injures ying xue yin ye,which causes deficient internal wind move;or phlegm and dampness pathogens injure spleen,and then causes spleen deficiency and dampness acumulates,which leads to phlegm and blood stasis blocks.Pathological factors are toxin,heat,deficiency,wind,phlegm,dampness and blood stasis.Pathogenesis is characterized by virulence,damp-heat and blood stasis stagnation,or spleen-kidney Yang deficiency,phlegm-toxin blocking collaterals.When the epidemic virus is heavy,the heat enters yingxue and consumes blood,it is given the treatment of"cooling blood and dispersing blood",clearing away heat and detoxification,cooling blood and activating blood circulation.Spleen and kidney yang deficiency and phlegm toxin obstructing collaterals,are given the treatment of invigorating spleen and warming kidney,resolving phlegm and purging turbidity,activating blood and dredging collaterals,and expelling qi.For those whose qi and yin are damaged by toxic pathogens and obstructed by collaterals,they should be treated with supplementing qi and nourishing yin,activating blood circulation and dredging blood vessels.
作者
刘汶
李梦缘
程红杰
牛昉
王仲霞
LIU Wen;LI Mengyuan;CHENG Hongjie;NIU Fang;WANG Zhongxia(Department of Hepatology,Beijing Traditional Chinese Medicine Hospital Affiliated to Capital Medical University,Beijing 100010,China;Spleen and Stomach Disease Center of Fangshan District,Beijing University of Chinese Medicine,Beijing 102400,China;Department of Hepatology,the 5th Medical Centre,Chinese PLA General Hospital,Beijing 100039,China)
出处
《中国中医药现代远程教育》
2019年第23期96-98,共3页
Chinese Medicine Modern Distance Education of China
关键词
急黄
肝衰竭
中医药疗法
fulminant jaundice
liver failure
therapy of traditional Chinese medicine
