摘要
目的探讨邢台山区食管癌的发病因素及其对策。方法选取2016年12月-2018年12月邢台山区来河北省民政总医院就诊的食管癌患者200例作为癌症组,同期选取非食管癌200例作为对照组,采用自制《食管癌的发病因素问卷》收集两组人员资料,并采用单因素分析和logistic回归分析食管癌的发病因素。结果癌症组少食新鲜蔬菜、少食新鲜水果、少食豆类、少食蛋类、喜食硬食、喜食腌制品、喜食烫食、喜食油炸食物、进食快、不规律饮食、吃霉变食物、饮酒、抽烟、饮用深井水和有胃肠炎、食管炎、家族肿瘤、胃和十二指肠溃疡病史的构成比明显高于对照组,差异有统计学意义(P<0.05)。癌症组和对照组性别、年龄、学历、婚姻、食用肉类,饮用奶类、喜食甜食、喜食辛辣食物的构成比比较,差异无统计学意义(P>0.05);logistic回归分析显示,少食新鲜蔬菜、少食豆类、喜食硬食、喜食腌制品、喜食烫食、喜食油炸食物、吃霉变食物、饮酒、抽烟、饮用深井水和有胃肠炎、食管炎、家族肿瘤、胃和十二指肠溃疡病史是食管癌的危险因素(P<0.05)。结论邢台山区食管癌的发病与多种因素有关,应重视有消化系统疾病的高危人群筛查。
Objective To explore the etiological factors and countermeasures of esophageal cancer(EC)in mountainous areas of Xingtai.Methods Two hundred EC patients who came from mountainous areas of Xingtai and were hospitalized in Hebei Provincial Civil Administration General Hospital from December 2016 to December 2018 were selected as the cancer group,while 200 persons without EC were simultaneously selected as the control group.A self-made questionnaire on etiological factors for EC was employed to collect the data of the two groups,and single factor analysis and logistic regression analysis were used to identify the etiological factors for EC.Results The proportions of seldom eating fresh vegetables,fresh fruits,beans and eggs,preferring hard food,pickled food,hot food and fried food,eating fast,irregular diet,eating moldy food,alcohol consumption,smoking,drinking deep well water and having a history of gastroenteritis,esophagitis,family tumor,gastric and duodenal ulcer were significantly higher in the cancer group than in the control group,and the differences were statistically significant(all P<0.05).But no statistically significant differences were found in the proportions of gender,age,educational background,marital status,meat consumption,milk consumption and preferring sweet and spicy food between the cancer group and the control group(all P>0.05).Logistic regression analysis revealed that seldom eating fresh vegetables and beans,preferring hard food,pickled food,hot food and fried food,eating moldy food,alcohol consumption,smoking,drinking deep well water and having a history of gastroenteritis,esophagitis,family tumor and gastric and duodenal ulcer were risk factors for EC(all P<0.05).Conclusions The incidence of EC in mountainous areas of Xingtai is related to many factors.It is necessary to pay special attention to the screening of high-risk population with digestive system diseases.
作者
耿惠
王玉强
韩素雅
路大鹏
齐增平
张传杰
李绵
GENG Hui;WANG Yu-qiang;HAN Su-ya;LU Da-peng;QI Zeng-ping;ZHANG Chuan-jie;LI Mian(Hebei Provincial Civil Administration General Hospital,Xingtai,Hebei 054000,China)
出处
《实用预防医学》
CAS
2020年第1期9-12,共4页
Practical Preventive Medicine
基金
河北省科学技术研究与发展计划项目(162777275)
关键词
邢台
山区
食管癌
发病因素
对策
Xingtai,mountainous area
esophageal cancer
etiological factor
countermeasure
