摘要
目的对2010-2017年三门峡市重症手足口病实验室检测结果进行分析,探讨重症病例病原分布特征。方法收集2010-2017年三门峡市重症手足口病检测数据,采用描述流行病学研究方法进行统计分析。结果在实验室检测的手足口病临床诊断病例1152例中,重症病例91例,其中80例肠道病毒感染,肠道病毒阳性率为87.91%。人肠道病毒71型(EV71)、柯萨奇病毒A16型(CA16)、肠道病毒通用型(PE)、其他和阴性重症率差异有统计学意义(χ2=56.852,P<0.01),散居和幼托儿童在不同病原中重症检出率不同(χ2=38.736、18.573,均P<0.01),在EV71、非EV71和阴性病例中重症检出率不同(χ2=56.251,P<0.01),均以EV71感染模式下的重症检出率为最高。重症病例的分布除在各年度差异较大外,在年龄及地区分布均衡一致。结论2010-2017年三门峡市手足口病重症病例中EV71感染是重要的危险因素,应从EV71监测入手,多措并举做好重症病例的识别和防控。
Objective To explore the pathogenic distribution characteristics of severe cases by analyzing the testing results about hand-foot-mouth disease(HFMD)in Sanmenxia City from 2010-2017.Methods The testing data of HFMD severe cases anmenxia City from 2010-2017 were collected and analyzed by descriptive epidemiological method.Results 1152 clinically diagnosed HFMD cases were detected in the laboratory.Among 91 severe cases,there were 80 cases of enterovirus infection,and the positive rate of enterovirus was 87.91%.There was statistically significant difference in the rate of severe cases among human enterovirus 71(EV71),Coxsackie virus A16(CA16),enterovirus universal(PE)and negative cases(χ2=37.594,P<0.01).There were statistically significant differences in the rate of severe cases between scattered children and nursery children in different pathogens(χ2=38.736,18.573,both P<0.01).There was statistically significant difference in the rate of severe cases among EV71,non EV71 and negative cases(χ2=56.251,P<0.01),and the rates of severe cases in EV71 infection were the highest.The distributions of severe cases were balanced in age and area except for the difference years.Conclusion EV71 infection is an important risk factor in severe cases of HFMD in Sanmenxia City from 2010-2017.Starting from EV71 monitoring,it is necessary to take multiple measures to identify and prevent severe cases.
作者
武恕星
武景福
崔法曾
杨洁
许苗苗
WU Shu-xing;WU Jing-ju;CUI Fa-zeng;YANG Jie;XU Miao-miao(Institute of Epidemiology,Sanmenxia Center for Disease Prevention and Control,Sanmenxia Henan,472000,China)
出处
《职业与健康》
CAS
2019年第23期3257-3260,共4页
Occupation and Health
关键词
手足口病
重症病例
肠道病毒
监测
Hand-foot-mouth disease
Severe case
Enteroviruses
Surveillance
