摘要
静息态功能磁共振成像(RS-fMRI)技术对阐释人类复杂脑网络提供了新媒介,尤其是在神经损伤脑机制分析方面取得了长足发展。腰椎间盘突出症(LDH)所致的慢性腰腿痛病变可引起大脑结构和功能的重塑。RS-fMRI技术对澄清大脑是如何参与慢性疼痛的调节机制方面发挥了重要作用,并有望为治疗LDH所致的慢性腰腿痛提供神经影像学指导。本文主要综述RS-fMRI脑功能连接分析方法在LDH所致的慢性疼痛中的最新应用进展,以期为临床治疗及研究LDH提供新思路。
In recent years,resting-state functional magnetic resonance imaging(RS-fMRI)technology has provided a new medium for interpreting human complex brain networks,especially in the brain mechanism analysis of nerve injuries.Chronic low back and leg pain caused by lumbar disc herniation(LDH)will lead to the structural and functional remodeling of the brain.RS-fMRI technology plays an important role in clarifying how the brain participates in the regulation of chronic pain,and the technology is expected to provide neuroimaging guidance for the treatment of chronic low back and leg pain caused by LDH.Herein the latest application progresses of RS-fMRI brain function connection analysis methods in chronic pain caused by LDH are mainly reviewed so as to provide new ideas for the clinical treatment and research of LDH.
作者
张天龙
赵继荣
陈祁青
马同
王闻奇
赵宁
薛旭
郭培尧
蔡毅
ZHANG Tianlong;ZHAO Jirong;CHEN Qiqing;MA Tong;WANG Wenqi;ZHAO Ning;XUE Xu;GUO Peiyao;CAI Yi(School of Clinical Traditional Chinese Medicine,Gansu University of Chinese Medicine,Lanzhou 730030,China;Gansu Provincial Hospital of TCM,Lanzhou 730050,China;Medical Imaging Center,Gansu Provincial Hospital of TCM,Lanzhou 730050,China)
出处
《中国医学物理学杂志》
CSCD
2019年第12期1421-1426,共6页
Chinese Journal of Medical Physics
基金
国家自然科学基金(81760877)
兰州市创新人才项目(2018-RC-99)
关键词
腰椎间盘突出症
慢性腰腿痛
静息态功能磁共振成像
功能连接
脑机制
lumbar disc herniation
chronic low back and leg pain
resting-state functional magnetic resonance imaging
brain mechanism
