摘要
目的研究血清总胆红素胱抑素C和N-端脑钠肽前体在慢性心力衰竭中的临床应用。方法通过选择2016年1月—2018年1月之间在本院进行就诊的慢性心力衰竭患者共100例,其中心功能Ⅱ级和Ⅲ至Ⅳ级的患者各50例作为试验组以及50例身体健康者作为对照组进行实验。在早晨对空腹患者进行抽血,抽静脉血3 mL,并在室温下静置30 min后使用分离血清上机进行TBIL、Cys C以及NT-proBNP等参数的测量。结果患有慢性心力衰竭的患者体内血清的TBIL与Cys C及NT-proBNP均呈现出正相关,研究结果表明了TBIL与Cys C及NT-proBNP三种参数均与慢性心力衰竭患者的心功能阶段划分以及病情严重程度相关联。结论通过对TBIL与Cys C及NT-proBNP的联合检测,能有助于明确慢性心力衰竭患者体内的情况,并且还能为后续的临床治疗、诊断以及预后提供一定程度的帮助。
Objective This experiment mainly studied the clinical application of serum total cholocystatin C and N-terminal natriuretic peptide precursors in chronic heart failure.Methods A total of 100 patients with chronic heart failure were treated in the hospital from January 2016 to January 2018.50 patients with central function Ⅱ and Ⅲ to Ⅳ were tested as experimental groups and 50 healthy patients as control groups.In the morning,the fasting patient was drawn blood,venous blood 3ml was taken,and 30 min was placed at room temperature.The isolated serum was used to measure TBIL,Cys C,and NT-proBNP parameters.Results The experimental results showed that the TBIL of serum in patients with chronic heart failure was positively correlated with Cys C and NT-proBNP.The results show that TBIL and Cys C and NT-proBNP are related to the cardiac function division and the condition of Yanzhongchengdu in patients with chronic heart failure.Conclusion Through the above research data analysis survey,it can be found that through the joint testing of TBIL and Cys C and NT-proBNP,it can help to clarify the situation in patients with chronic heart failure.And it can also provide a certain degree of help for subsequent clinical treatment,diagnosis and prognosis.
作者
梁景彪
LIANG Jingbiao(Clinical Laboratory,Yulin Second People's Hospital,Yulin Guangxi 537000,China)
出处
《中国卫生标准管理》
2019年第21期98-99,共2页
China Health Standard Management
关键词
血清总胆红素
慢性心力衰竭
临床应用
脑钠肽前体
离心血清分离
标志物检测
serum total bilirubin
chronic heart failure
clinical application
brain natriuretic peptide precursor
Separation of serum by centrifugation
detection of markers