摘要
目的观察自拟舒肝养胃汤治疗胃食管反流病的临床效果。方法随机选取2016年8月至2018年8月本院胃食管反流病患者48例为研究对象,随机分为自拟舒肝养胃汤治疗组(治疗组)和雷贝拉唑胶囊单独治疗组(对照组),每组24例,统计两组患者的中医证候积分、临床症状积分、临床疗效。结果治疗前,两组患者中医证候积分比较差异无统计学意义;与治疗前相比,两组患者治疗后的反酸嗳气、双肋疼痛、食欲不振、胃脘胀满、大便不畅、胸闷积分均显著降低(P<0.05);与对照组相比,治疗组患者治疗后的反酸嗳气、双肋疼痛、食欲不振、胃脘胀满、大便不畅、胸闷积分均显著降低(P<0.05)。治疗前,两组患者临床症状积分比较差异无统计学意义;与治疗前相比,两组患者治疗后的反酸、烧心、反流、胸痛积分均明显降低(P<0.05);与对照组相比,治疗组患者治疗后的反酸、烧心、反流、胸痛积分均明显降低(P<0.05)。治疗组患者中治愈8例、显效10例、有效5例,治疗的总有效率为95.8%(23/24);对照组患者中治愈5例、显效8例、有效6例,治疗的总有效率为79.2%(19/24),治疗组患者治疗的总有效率明显高于对照组(P<0.05)。结论自拟舒肝养胃汤治疗胃食管反流病的临床效果好,值得在临床推广应用。
Objective To observe the clinical effect of Shugan Yangwei decoction on gastroesophageal reflux disease. Methods 48 cases of patients with gastroesophageal reflux disease were randomly selected from August 2016 to August 2018. They were randomly divided into Shugan Yangwei decoction treatment group(treatment group) and rabeprazole capsule treatment group(control group), 24 cases in each group. The scores of TCM syndromes, clinical symptoms and clinical efficacy of the two groups were counted. Results There was no significant difference in scores of TCM syndromes between the twogroups before treatment. Compared with before treatment, the scores of acid regurgitation, bilateral rib pain, loss of appetite, epigastric fullness, obstruction of stool and chest tightness in the two groups were significantly decreased after treatment(P<0.05). After treatment, compared with the control group, the scores of acid regurgitation, bilateral rib pain, loss of appetite, epigastric fullness, dyspepsia and chest in the treatment group were significantly decreased(P<0.05). The tightness score decreased significantly(P<0.05). Compared with before treatment,the scores of acid regurgitation, heartburn, reflux and chest pain in the two groups after treatment were significantly lower(P<0.05). After treatment,the scores of acid regurgitation, heartburn, reflux and chest pain in the treatment group were significantly lower than those in the control group(P<0.05). In the treatment group, 8 cases were cured, 10 cases were markedly effective and 5 cases were effective. The total effective rate was 95.8%(23/24). In the control group, 5 cases were cured, 8 cases were markedly effective and 6 cases were effective and the total effective rate was 79.2%(19/24). The total effective rate of the treatment group was significantly higher than that of the control group(P<0.05). Conclusion The self-made Shugan Yangwei decoction has good clinical effect in treating gastroesophageal reflux disease, and it is worth popularizing and applying in clinic.
作者
陈伟
刘静
熊云峰
廖文莲
易献春
Chen Wei;Liu Jing;Xiong Yunfeng;Liao Wenlian;Yi Xianchun(Department of Inpatient,Yichun Integrated Chinese andWestern Hospital,Yichun,Jiangxi,336000,China)
出处
《当代医学》
2019年第34期12-15,共4页
Contemporary Medicine
关键词
自拟舒肝养胃汤
胃食管反流病
临床效果
Self-made Shugan Yangwei decoction
Gastroesophageal reflux disease
Clinical effect
