摘要
目的分析妊娠合并甲状腺功能减退患者临床资料,探讨其对妊娠结局和并发症的影响。方法以2017年1月~2019年1月来我院治疗的100例妊娠合并甲减患者作为观察组,以同期在我院接受检查并分娩的100例正常孕妇作为对照组,分别于孕3个月、孕6个月、孕9个月和产后7d用放射免疫法检测孕妇血中的TSH水平,比较两组的妊娠结局和并发症发生情况。结果不同孕期TSH水平比较,差异均有统计学意义(P<0.05),观察组产妇不同孕期的TSH水平均高于对照组,差异有统计学意义(P<0.05);观察组产妇早产率、流产率、剖宫产率、新生儿窒息率显著高于对照组,差异有统计学意义(P<0.05),观察组9例新生儿被诊断为甲状腺功能减退,对照组无新生儿甲状腺功能减退发生,两组比较差异有统计学意义(P<0.05);观察组并发症发生率为22%,对照组为8%,差异有统计学意义(P<0.05)。结论对妊娠妇女应及时筛查甲状腺功能,以减少不良妊娠结局和产科并发症的发生,保障母婴健康。
Objective To analyze the clinical data of patients with pregnancy combined with hypothyroidism and to explore its effect on pregnant outcomes and complications.Methods 100 patients with pregnancy combined with hypothyroidism who were treated in our hospital from January 2017 to January 2019 were selected as the observation group,while 100 normal pregnant women who underwent examinations and delivery in our hospital during the same period were set as the control group.Radioimmunoassay was used to detect TSH levels in maternal blood on 3 months of pregnancy,6 months of pregnancy,9 months of pregnancy and 7 days after delivery.Pregnant outcomes and complications were compared between the two groups.Results There were statistical significant differences in TSH levels in different pregnant period(P<0.05).The TSH levels in different pregnant period of pregnant women in the observation group were all higher than those in the control group,and the differences were statistically significant(P<0.05).Maternal preterm birth rate,abortion rate,cesarean section rate and neonatal asphyxia rate were significantly higher in the observation group than in the control group,and the differences were statistically significant(P<0.05).Nine neonates in the observation group were diagnosed with hypothyroidism,while no neonates in the control group had hypothyroidism,and the differences were statistically significant between two groups(P<0.05).The incidence of complication in the observation group was 22%,and that in the control group was 8%.The difference was statistically significant(P<0.05).Conclusion Pregnant women should be screened for thyroid function in time to reduce adverse pregnant outcomes and obstetric complications and to ensure maternal and child health.
作者
光晓珍
GUANG Xiaozhen(Department of Obstetrics and Gynecology,Changping District Hospital,Beijing 102200,China)
出处
《中国医药科学》
2019年第22期76-78,91,共4页
China Medicine And Pharmacy
