摘要
目的探讨接受碘造影剂检查患者发生造影剂肾病的临床危险因素。方法回顾性分析331例接受碘造影剂检查患者,其中造影剂肾病组31例,非造影剂肾病组298例,分析2组患者的临床资料。应用多因素Logistic回归分析危险因素。结果在接受碘造影剂检查患者中,造影剂肾病发病率为9.97%。与非造影剂肾病组相比,造影剂肾病组患者平均年龄、造影前肌酐值、造影后肌酐值及应用造影剂剂量均明显增加(P<0.05)。造影剂肾病组患者进行动脉造影检查比例明显增加,且合并慢性肾脏病3期以上、合并高血压及合并糖尿病比例明显增加(P<0.05)。Logistic回归分析提示,年龄、造影前肌酐值及合并糖尿病是造影剂肾病的独立危险因素(OR值分别为1.12、1.36、9.05,均P<0.05)。结论年龄、基础肾功能及是否合并糖尿病是发生造影剂肾病的危险因素。
Objective To investigate the clinical risk factors of contrast-induced nephropathy(CIN) in patients. Methods We conducted a retrospective observational study to analyze the 331 patients who using contrast for examination. These patients were divided into CIN group(n=31) and no-CIN(n=298) group. Clinical baseline data in the two groups were analyzed, and the risk factors were determined by multivariate logistic regression analysis.Results The incidence of CIN was 9.97%. Compared with the non-CIN group, the average age, the value of creatinine before or after using contrast, and the dosage of contrast were significantly increased in the CIN group(P <0.05). In the CIN group, the proportion of arteriography, chronic renal disease over 3 stages, hypertension and diabetes significantly increased(P<0.05). Multivariate logistic regression analysis showed that age, basic renal function and diabetes mellitus were the independent risk factors for CIN(OR=1.12, 1.36, 9.05, respectively, all P<0.05).Conclusion Age, basic renal function and diabetes mellitus are risk factors for CIN.
作者
孙有保
Sun Youbao(Department of Gerontology,the People's Hospital of Wuzhi County,Jiaozuo city,Henan 454950,China)
出处
《实用医学影像杂志》
2019年第6期574-576,共3页
Journal of Practical Medical Imaging
关键词
肾病
危险因素
造影剂
Nephropsis
Risk factor
Contrastmedia
