摘要
随着经济的发展人民生活水平的提高,我国糖尿病的患病率也显著增加,而糖尿病性黄斑水肿(DME)是严重影响患者视力导致视力丧失的最重要因素。DME是由于糖尿病损害眼底微血管结构,黄斑区内毛细血管渗漏增加导致细胞外液体的积聚而产生;DME常见分类有局限性、弥漫性以及混合性黄斑水肿3类;目前DME治疗方法有激光光凝、玻璃体腔注药(抗VEGF药物、曲安奈德)、手术治疗(单纯玻璃体切除或联合内界膜剥除)、联合治疗(激光联合抗VEGF药物或曲安奈德)以及中医药等新兴治疗方法。DME治疗中激光治疗向着损伤小的方向发展,药物治疗趋向长效及减小副作用,联合治疗往往能取得更好的疗效,也是目前较为热门的选项,一些新型药物及新疗法辅助传统疗法的应用也值得期待。
With economy development and the improvement of people’s living standards, the prevalence of diabetes also increases significantly. Diabetic macular edema(DME) could severely affect patients’ visual acuity and is a major cause for vision loss. DME is caused by impairment of the micro-vascular structure by diabetes, as well as the accumulation of extra celluar fluid due to macular capillary leakage. DME could be commonly divided into 3 types, the limited, diffuse and mixed type. Current treatment methods for DME include laser photocoagulation, intra-vitreous injection of anti-VEGF drugs or Triamcinolone acetonide, surgery(simple vitrectomy or combined with limiting membrane peeling), combined therapy(laser photocoagulation combined with anti-VEGF drugs or Triamcinolone acetonide) and new therapy such as traditional Chinese medicine. Among all the treatments, laser photocoagulation tends to be more mini-invasive, the drug therapy tends to have longer effect and less side-effect, the combined therapy can usually result in better therapeutic effect and thus a prefer treatment option, some new drugs and assisted therapy are also worth to be expected.
作者
王鑫
孙长文
Wang Xin;Sun Changwen(The Eye Hospital of Nanjing Medical University,Jiangsu 210000,China;The Zhijiang Branch of the Zhehiang Provincial Eye Hospital,Hangzhou 310000,China)
出处
《临床眼科杂志》
2019年第6期560-564,共5页
Journal of Clinical Ophthalmology
